| 赵银娇,滕兆伟,李铁山.超声引导下富血小板血浆注射治疗肩袖部分撕裂的临床疗效观察[J].中国康复,2024,39(4):212-217 |
| 超声引导下富血小板血浆注射治疗肩袖部分撕裂的临床疗效观察 |
| Clinical efficacy of ultrasound-guided injection of platelet-rich plasma for partial rotator cuff tears |
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| DOI： |
| 中文关键词: 富血小板血浆 超声引导注射 肩袖部分撕裂 |
| 英文关键词: platelet-rich plasma ultrasound-guided injection partial rotator cuff tear |
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| 中文摘要: |
| 目的：观察超声引导下富血小板血浆注射治疗肩袖部分撕裂的临床疗效。方法：42例肩袖部分撕裂患者随机分为观察组和对照组各21例，2组各有1例脱落，最终各20例完成研究。观察组给予超声引导下富血小板血浆注射治疗，对照组给予超声引导下玻璃酸钠注射治疗。2组均每周治疗1次，共3次。分别于治疗前、治疗后1、3及6个月，采用视觉模拟评分（VAS）、Constant-Murley评分（CMS）和美国肩肘外科医师评分（ASES）对2组患者的肩关节疼痛及功能情况进行评估，并记录不良事件发生情况。同时，于治疗前和治疗后6个月对所有患者进行超声检查记录撕裂大小以评估肌腱结构完整性。结果：在治疗后1个月，2组的VAS、CMS、ASES评分差异无统计学意义。在治疗后3个月和6个月，观察组的VAS评分较对照组降低、CMS和ASES评分较对照组升高（均P＜0.05），在治疗后6个月，观察组的撕裂尺寸较对照组降低（均P＜0.05）；在治疗后随访的任何时期，2组患者的VAS均较治疗前降低、CMS和ASES评分均较治疗前升高（均P＜0.05）；观察组的撕裂尺寸较治疗前降低（P＜0.05），而对照组的改变无统计学意义。结论：超声引导下富血小板血浆注射不仅可显著改善肩袖部分厚度撕裂患者肩关节疼痛和功能，而且减小撕裂尺寸，促进撕裂肌腱组织再生。 |
| 英文摘要: |
| Objective: To observe the clinical efficacy of ultrasound-guided injection of platelet-rich plasma for partial rotator cuff tears. Methods: Totally, 40 patients with partial rotator cuff tears were randomized to platelet-rich plasma group and sodium hyaluronate group, 20 patients in each group. Both groups were given injection once a week for a total of 3 times. The outcome measures included the Visual Analogue Scale (VAS), Constant-Murley Score (CMS) and American Shoulder and Elbow Surgeons Score (ASES) which were obtained from patients at the base line and 1, 3, 6 months after treatment. At the same time, tear sizes were measured by ultrasound at the base line and 6 months after treatment. Results: The VAS, CMS and ASES had no significant change between the two groups at 1st month after treatment. At 3rd and 6th month after treatment, the VAS scores in the platelet-rich plasma group were lower than those in the sodium hyaluronate group, and CMS and ASES scores in the platelet-rich plasma group were higher than those in the sodium hyaluronate group. At 3rd and 6th month after treatment, the tear sizes in the platelet-rich plasma group were lower than those in the sodium hyaluronate group. At any time of post-treatment follow-up, in the two groups, the VAS scores were lower than those at the base line (P<0.05) and the CMS and ASES scores were higher than those at the base line (P<0.05). Tear sizes in the platelet-rich plasma group were lower than those at the base line (P<0.05), but tear sizes had no significant change in the sodium hyaluronate group. No serious adverse events related to the injection therapy were reported. Conclusions: Ultrasound-guided injection of platelet-rich plasma not only significantly improves shoulder pain and function in patients with partial rotator cuff tear, but also reduces the tear size and promotes regeneration of torn tendon tissue. |
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