| 樊蕴辉,伊红丽,李立群,曹国富,沈海涛.同型半胱氨酸、叶酸及VitB12与血管性痴呆的相关性研究[J].中国康复,2012,27(2):95-96 |
| 同型半胱氨酸、叶酸及VitB12与血管性痴呆的相关性研究 |
| Relationship Between Homocysteine, Folate,Vitamin B12 and Vascular Dementia |
| |
| DOI： |
| 中文关键词: 血管性痴呆 同型半胱氨酸 相关性 |
| 英文关键词: vascular dementia homocysteine relationship |
| 基金项目: |
|
| 摘要点击次数: 7981 |
| 全文下载次数: 6194 |
| 中文摘要: |
| 目的：探讨血浆同型半胱氨酸(Hcy)、叶酸(FA)、VitB12与血管性痴呆(VaD)的相关性。方法：检测VaD患者86例（VaD组），非VaD患者87例（非VaD组），健康体检正常者90例（正常组）血浆Hcy、FA、VitB12浓度。并对3组受检者进行简易智能状态量表（MMSE）评定。结果：VaD组患者Hcy浓度显著高于非VaD组及正常组(P <0.01)。FA、VitB12浓度与Hcy浓度负相关。血浆Hcy、FA、VitB12水平与VaD、MMSE得分显著相关(P <0.01)。结论：VaD高危人群应定期检测Hcy浓度，推荐服用VitB12和FA可预防VaD的发生。 |
| 英文摘要: |
| Objective: To investigate the relationship between plasma homocysteine (Hcy), folate,vitamin B12 and vascular dementia (VaD). Methods: The plasma levels of Hcy, folate, vitamin B12 and MMSE were measured in 86 VaD patients, 87 non-VaD cerebral vascular disease patients, and 90 age-matched normal controls of Affiliated Hospital, North China Coal Medical University.Results: The plasma Hcy levels were significantly increased in the VaD group than non-VaD cerebral vascular disease group and normal controls (P<0.01). The Hcy level was negatively related with folate and VitB12 levels. They all significantly correlated with VaD and the MMSE score (P<0.01). Conclusion: The levels of Hcy, folate and vitamin B12 were significantly correlated with VaD. |
|
查看全文
下载PDF阅读器 HTML全文 |
| 关闭 |
|
|
|
