| 孙道法,张帆,谢均灿,张运良,危晴天,许刚,李晓鹏,陈旭,蒋伟,舒凯.高压氧对重型颅脑损伤术后患者长期预后的影响[J].中国康复,2012,27(4):249-251 |
| 高压氧对重型颅脑损伤术后患者长期预后的影响 |
| Effect of hyperbaric oxygen on long-term outcome of patients in severe traumatic brain injury |
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| DOI： |
| 中文关键词: 重型颅脑损伤 高压氧 癫痫 生存质量指数 |
| 英文关键词: severe traumatic brain injury HBO epilepsy QLI |
| 基金项目:湖北省自然科学基金面上项目（2009CDB291） |
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| 中文摘要: |
| 目的:探讨高压氧（HBO）对重型颅脑损伤开颅术后疗效及预后的影响。方法：重型颅脑损伤后行标准外伤大骨瓣开颅术后患者97例，术后接受HBO治疗3个月，按是否坚持完成HBO治疗分为完成组61例和未完成组36例。随访5年，观察2组并发癫痫的比率、癫痫发作周期、死亡人数、格拉斯哥昏迷量表（GCS）及生存质量指数（QLI）评分。结果：2组术后24h及术后3个月GCS评分均明显高于术前（P<0.05），术后3个月完成组GCS及QLI评分明显高于未完成组（P<0.05），完成组出现继发癫痫及死亡例数明显低于未完成组（P<0.05）；癫痫患者发作周期明显长于未完成组（P<0.05）。结论：重型颅脑损伤患者行标准外伤大骨瓣开颅术后配合标准疗程的HBO治疗可明显降低继发癫痫的比率，提高生存质量。 |
| 英文摘要: |
| Objective: To investigate the effect of hyperbaric oxygen (HBO) treating severe traumatic brain injury after craniotomy. Methods:97 patients of severe traumatic brain injury receiving standard large trauma craniotomy received hyperbaric oxygen and were divided into completed group （n=61）and no-completed group （n=36）according to whether completing hyperbaric oxygen treatment or not. In a follow-up visit of 5 years, incidence of posttraumatic seizure,GCS score and quality of life index (QLI) score of two groups were observed.Results: GCS score of two groups 24h and 3 months after operation were significantly higher than that of before（P<0.05）. 3 months after operation GCS and QLI scores in completed group were much higher than that of no-completed group（P<0.05）.The incidence of posttraumatic seizure and death cases in completed group were significantly lower than that of no-completed group（P<0.05）, and attack cycle was much longer than that of no-completed group（P<0.05）.Conclusion: Giving standard large trauma craniotomy and hyperbaric oxygen therapy to patients of severe traumatic brain injury can significantly decrease the incidence of posttraumatic seizure and death, improve the quality of life. |
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