| 余维巍,夏秦.长期家庭氧疗对慢性阻塞性肺病的影响[J].中国康复,2012,27(4):280-281 |
| 长期家庭氧疗对慢性阻塞性肺病的影响 |
| Effect of Long-term oxygen therapy on chronic obstructive pulmonary disease |
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| DOI： |
| 中文关键词: 慢性阻塞性肺病 家庭氧疗 |
| 英文关键词: chronic obstructive pulmonary disease long-term oxygen therapy |
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| 中文摘要: |
| 目的：观察长期家庭氧疗（LTOT）对慢性阻塞性肺病(COPD)患者气道壁厚度及肺功能的影响。方法：中重度COPD患者45例，随机分为家庭氧疗组（氧疗组）和对照组各20例，2组均接受常规药物治疗，氧疗组加用长期家庭氧疗。治疗前后行高分辨率螺旋CT（HRCT）扫描测试2组的气道壁厚度（WT）和气道壁相对面积值（WA%）及肺功能测试。结果：治疗2年后，对照组WT、WA%较治疗前明显增加(P<0.05)，FEV1/FVC较治疗前明显降低(P<0.05)，氧疗组各指标治疗前后比较差异无统计学意义。结论：长期家庭氧疗能有效改善COPD患者的气道重建及延缓患者的肺功能恶化。 |
| 英文摘要: |
| Objective: To explore the long-term oxygen therapy on bronchial wall thickness and lung function of chronic obstructive pulmonary disease. Methods：Forty patients with moderate severe chronic obstructive pulmonary disease were randomly divided into LTOT group and control group.Both groups were given conventional rehabilitation,and LTOT group was given long term oxygen therapy additionally. Pulmonary function test and HRCT scan were assessed.Results:After two years of treatment,the WT and WA% score of control group were increased than that of before(P<0.05). FEV1/FVC score of control group were lower than that of before(P<0.05).Every score of LTOT group were not significantly different from that of before. Conclusion：Long-term oxygen therapy could be effectively ameliorate the airway remodeling of patients with chronic obstructive pulmonary disease and reduce the degradation of lung function. |
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