rTMS结合脑电生物反馈对孤独症谱系障碍儿童刻板行为的疗效

李梦青; 姜志梅; 李雪梅; 郭岚敏

文章摘要

李梦青,姜志梅,李雪梅,郭岚敏.rTMS结合脑电生物反馈对孤独症谱系障碍儿童刻板行为的疗效[J].中国康复,2018,33(2):114-117

rTMS结合脑电生物反馈对孤独症谱系障碍儿童刻板行为的疗效

rTMS and neurofeedback treatment on stereotyped behavior of children with autism spectrum disorder

DOI：

中文关键词: 孤独症谱系障碍重复经颅磁刺激脑电生物反馈刻板行为

英文关键词: autism spectrum disorder repetitive transcranial magnetic stimulation neurofeedback stereotyped behavior

基金项目:

作者	单位
李梦青	佳木斯大学附属第三医院儿童保健科，黑龙江佳木斯 154003
姜志梅	佳木斯大学附属第三医院儿童保健科，黑龙江佳木斯 154003
李雪梅	佳木斯大学附属第三医院脑瘫康复科，黑龙江佳木斯 154003
郭岚敏	佳木斯大学附属第三医院儿童保健科，黑龙江佳木斯 154003

摘要点击次数: 8755

全文下载次数: 6339

中文摘要:

目的：探讨重复经颅磁刺激（rTMS）结合脑电生物反馈（NFB）对孤独症谱系障碍（ASD）儿童刻板行为的疗效分析。方法：ASD儿童60例，随机分成4组各15例：对照组（常规康复训练），rTMS组（常规康复训练+rTMS），NFB组（常规康复训练+NFB），rTMS-NFB组（常规康复训练+rTMS+NFB，且NFB紧随rTMS之后），疗程12周，治疗前后用重复刻板行为量表（RBS-R）及孤独症行为检查量表（ABC）进行评估。结果：治疗12周后，4组RBS-R评分及ABC评分均较治疗前明显减少（均P<0.05）；且TMS组、NFB组、rTMS-NFB组RBS-R评分及ABC评分均明显低于对照组（均P<0.05），rTMS-NFB组RBS-R评分及ABC评分均明显低于rTMS组及NFB组（均P<0.05），rTMS组及NFB组RBS-R评分及ABC评分2组间比较差异无统计学意义。结论：常规康复训练、rTMS、NFB及rTMS-NFB对ASD儿童刻板行为的改善均有一定的促进作用；rTMS与NFB对其疗效相当；但rTMS-NFB的疗效明显优于rTMS、NFB单独治疗。

英文摘要:

Objective: To explore the effectiveness of transcranial magnetic stimulation (rTMS) combined with neurofeedback (NFB) on stereotyped behavior of children with autism spectrum disorder (ASD). Methods: Sixty children with ASD were randomly divided into four groups (n=15 for each group): the control group receiving conventional rehabilitation training, the rTMS group receiving rTMS treatment additionally, the NFB group receiving NFB treatment additionally, and the rTMS-NFB group receiving rTMS and NFB treatment additionally. The rTMS was followed by NFB in rTMS-NFB group. After 12 weeks of treatment, all patients were assessed by repetitive behavior scale-revised (RBS-R) and autism behavior checklist (ABC). Results: The scores of RBS-R and ABC were decreased in each group after treatment (P<0.05). There was no significant differences between the rTMS group and the NFB group (P>0.05). The scores of RBS-R and ABC in the rTMS-NFB group were decreased more significantly than the NFB group and rTMS group (P<0.05). Conclusion: The conventional rehabilitation training, rTMS, NFB and rTMS-NFB may have some effects on stereotyped behavior of children with ASD. There is no significant differences between the rTMS and NFB groups. And the effect of the rTMS-NFB is better than the rTMS or NFB alone.

查看全文下载PDF阅读器 HTML全文

关闭