文章摘要
郭艮春,朱振华,李万浪.神经松动术联合甲钴胺治疗糖尿病周围神经病变临床疗效观察[J].中国康复,2018,33(2):118-121
神经松动术联合甲钴胺治疗糖尿病周围神经病变临床疗效观察
Clinical effects of neurodynamic technique combined with mecobalamine for diabetic peripheral neuropathy
  
DOI:
中文关键词: 糖尿病周围神经病变  神经松动术  甲钴胺  生活质量
英文关键词: diabetic peripheral neuropathy  neurodynamic technique  mecobalamine  quality of life
基金项目:
作者单位
郭艮春 盐城市第三人民医院康复医学科江苏 盐城 224002 
朱振华 盐城市第三人民医院康复医学科江苏 盐城 224002 
李万浪 盐城市第三人民医院康复医学科江苏 盐城 224002 
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中文摘要:
      目的:探讨神经松动术联合甲钴胺治疗糖尿病周围神经病变的临床疗效。方法:选择糖尿病周围神经病变患者90例,将其随机分为观察组45例、对照组45例。对照组给予甲钴胺治疗,观察组在此基础上施加神经松动术。3个月后进行疗效评价。观察指标包括临床疗效总有效率、简化McGill量表测评、神经传导速度及SF-36生活质量量表测评。结果:经过3个疗程治疗后,观察组的临床疗效总有效率明显高于对照组(91.1%、73.3%,均P<0.05);观察组的疼痛评级指数(PRI)总分、视觉模拟评分(VAS)和现有疼痛强度(PPI)评分降低幅度均优于对照组(均P<0.05);观察组的运动神经传导速度MNCV和感觉神经传导速度SNCV提高程度均高于对照组(均P<0.05);SF-36量表中8个维度的评分及总分比较,观察组均高于与对照组,在生理机能、生理职能、躯体疼痛、情感职能上的组间差异有统计学意义(均P<0.05),其他4项维度评分及总分的差异无统计学意义。结论:神经松动术联合甲钴胺治疗糖尿病周围神经病变疗效满意,值得临床推广。
英文摘要:
      Objective: To study the clinical effects of neurodynamic technique combined with mecobalamine on diabetic peripheral neuropathy. Methods: Ninety patients with diabetic peripheral neuropathy were randomly divided into experimental group and control group, 45 patients in each group. Patients in the control group were treated with mecobalamin, 0.5 mg each time, three times a day. In addition to the mecobalamine, patients in the experimental group were treated with neurodynamic technique. After 3 months we measured clinical efficacy rate, the simplified McGill scale, nerve conduction velocity (NCV) and the Mos 36-item Short Form Health Survey (SF-36). Results: After the treatment, the clinical efficacy rate in the experimental group was significantly higher than in the control group (91.1% vs.73.3%, P<0.05). The total scores of pain rating index (PRI), visual analogue scale (VAS) and present pain intensity (PPI) in the experimental group were significantly lower than in the control group (P<0.05). The motor NCV and sensory NCV in the experimental group were significantly faster than in the control group (P<0.05). The scores of the 8 domains and total score of SF-36 in the experimental group were significantly higher than in the control group. There were significant differences in the physical functioning, role-physical, bodily pain and role-emotional between the two groups (P<0.05), but there were no significant differences in the rest four domains and total score (P>0.05). Conclusion: Neurodynamic technique combined with mecobalamine for diabetic peripheral neuropathy is more effective, and worth promoting.
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