文章摘要
王丽娟,刘欣,王红霞,刘荧,吕娜,李皓.计算机辅助训练对轻度认知功能障碍的干预性研究[J].中国康复,2019,34(9):473-476
计算机辅助训练对轻度认知功能障碍的干预性研究
Efficacy of computer-assisted cognitive training in mild cognitive impairment
  
DOI:
中文关键词: 认知训练  轻度认知功能障碍  干预
英文关键词: cognitive training  mild cognitive impairment  intervention
基金项目:北京市中关村医院科研培育专项(201704)
作者单位
王丽娟 中关村医院神经内科北京 100190 
刘欣 中关村医院神经内科北京 100190 
王红霞 中关村医院神经内科北京 100190 
刘荧 中关村医院神经内科北京 100190 
吕娜 中关村医院神经内科北京 100190 
李皓 中关村医院神经内科北京 100190 
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中文摘要:
  目的:探究计算机辅助训练对轻度认知功能障碍(MCI)的干预性研究。方法:连续收集年龄≥60岁的轻度认知功能障碍(MCI)患者100例,随机分为治疗组与对照组各50例,对照组给予健康宣教与危险因素控制,治疗组在对照组的基础上联合计算机辅助认知训练,每周3次,每次30min,共6个月。在治疗前、治疗后3、6、12个月,采用蒙特利尔认知评估量表(MoCA)和工具性日常生活能力(IADL)量表进行评价。结果:在治疗3、6、12个月后,治疗组MoCA值均明显高于干预前及同时间对照组(P<0.01),在治疗6个月、12个月时对照组MoCA值较干预前明显升高(P<0.01),2组之间存在交互作用(F=158.6,P<0.01)。治疗12个月后,2组IADL评分均明显高于治疗前(P<0.01),且治疗组的IADL明显高于对照组(P<0.01)。结论:对MCI患者进行早期筛查、健康宣教、危险因素控制及计算机辅助认知功能训练的综合干预,可有效改善认知功能障碍,减缓认知功能障碍发展,提高生活质量。
英文摘要:
  Objective: To investigate the intervention of computer-assisted cognitive training in mild cognitive impairment (MCI). Methods: One hundred MCI patients aged 60 years old or over were randomly divided into two group: observation group (50 cases), accepting computer-assisted cognitive training, health education and risk factors control; control group (50 cases), only accepting health education and risk factors control. The computer-assisted cognitive training was given 30 min every time, 3 times every week for 6 months. The cognitive and psychosocial assessments were performed by MoCA and IADL scales at baseline (M0), and 3 months (M3), 6 months (M6), and 12 months (M12) post intervention. Results: The average MoCA scores in the observation group were significantly higher after treatment for 3, 6 and 12 months than those before intervention and control group correspondingly (P<0.01). At M6 and M12, the MoCA scores in the control group were significantly higher than those before intervention (P<0.01). A crossover effect occurred between the two groups in multiple repeated measures (F=158.6, P<0.01). At M12, the IADL scores in both groups were significantly higher than before intervention (P<0.01), and those in the observation group were significantly higher than in control group (P<0.01). Conclusion: The comprehensive cognitive intervention can effectively improve cognitive deficit, reduce cognitive decline and improve the quality of life.
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