| 王丽娟,刘欣,王红霞,刘荧,吕娜,李皓.计算机辅助训练对轻度认知功能障碍的干预性研究[J].中国康复,2019,34(9):473-476 |
| 计算机辅助训练对轻度认知功能障碍的干预性研究 |
| Efficacy of computer-assisted cognitive training in mild cognitive impairment |
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| DOI： |
| 中文关键词: 认知训练 轻度认知功能障碍 干预 |
| 英文关键词: cognitive training mild cognitive impairment intervention |
| 基金项目:北京市中关村医院科研培育专项（201704） |
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| 中文摘要: |
| 目的：探究计算机辅助训练对轻度认知功能障碍(MCI)的干预性研究。方法：连续收集年龄≥60岁的轻度认知功能障碍（MCI）患者100例，随机分为治疗组与对照组各50例，对照组给予健康宣教与危险因素控制，治疗组在对照组的基础上联合计算机辅助认知训练，每周3次，每次30min，共6个月。在治疗前、治疗后3、6、12个月，采用蒙特利尔认知评估量表（MoCA）和工具性日常生活能力（IADL）量表进行评价。结果：在治疗3、6、12个月后，治疗组MoCA值均明显高于干预前及同时间对照组（P＜0.01），在治疗6个月、12个月时对照组MoCA值较干预前明显升高（P＜0.01），2组之间存在交互作用（F=158.6，P＜0.01）。治疗12个月后，2组IADL评分均明显高于治疗前（P＜0.01），且治疗组的IADL明显高于对照组（P＜0.01）。结论：对MCI患者进行早期筛查、健康宣教、危险因素控制及计算机辅助认知功能训练的综合干预，可有效改善认知功能障碍，减缓认知功能障碍发展，提高生活质量。 |
| 英文摘要: |
| Objective: To investigate the intervention of computer-assisted cognitive training in mild cognitive impairment (MCI). Methods: One hundred MCI patients aged 60 years old or over were randomly divided into two group: observation group (50 cases), accepting computer-assisted cognitive training, health education and risk factors control; control group (50 cases), only accepting health education and risk factors control. The computer-assisted cognitive training was given 30 min every time, 3 times every week for 6 months. The cognitive and psychosocial assessments were performed by MoCA and IADL scales at baseline (M0), and 3 months (M3), 6 months (M6), and 12 months (M12) post intervention. Results: The average MoCA scores in the observation group were significantly higher after treatment for 3, 6 and 12 months than those before intervention and control group correspondingly (P<0.01). At M6 and M12, the MoCA scores in the control group were significantly higher than those before intervention (P＜0.01). A crossover effect occurred between the two groups in multiple repeated measures (F=158.6, P<0.01). At M12, the IADL scores in both groups were significantly higher than before intervention (P<0.01), and those in the observation group were significantly higher than in control group (P<0.01). Conclusion: The comprehensive cognitive intervention can effectively improve cognitive deficit, reduce cognitive decline and improve the quality of life. |
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