文章摘要
刘晶涛,董大伟,陆巍,陈俊杉.神经肌肉电刺激对ICU患者肌力及临床结局影响的系统评价[J].中国康复,2019,34(11):599-604
神经肌肉电刺激对ICU患者肌力及临床结局影响的系统评价
Influences of Neuromuscular Electrical Stimulation on Muscle Strength and Clinical Outcomes in ICU Patients: A Systematic Review
  
DOI:
中文关键词: 神经肌肉电刺激  ICU获得性衰弱  重症监护室  危重症患者  系统评价
英文关键词: neuromuscular electrical stimulation  ICU-AW  intensive care units  critical illness  systematic review
基金项目:
作者单位
刘晶涛 南京大学医学院附属鼓楼医院重症医学科南京 210008 
董大伟 南京大学医学院附属鼓楼医院重症医学科南京 210008 
陆巍 南京大学医学院附属鼓楼医院护理部南京 210008 
陈俊杉 南京大学医学院附属金陵医院重症医学科南京210002 
摘要点击次数: 1292
全文下载次数: 821
中文摘要:
      目的:系统评价神经肌肉电刺激对ICU患者肌力及临床结局的干预效果。方法:计算机检索Cochrane Library、Web of Science、PubMed、中国知网、维普以及万方数据库中从建库至2018年12月公开发表的关于神经肌肉电刺激在ICU患者中应用效果的随机对照试验,由两名研究人员独立对文献筛选、数据提取和文献质量进行评价。采用Revman5.3软件对符合质量标准的文献中的结局指标进行Meta分析。结果:共纳入14篇文献。6篇文献报告了患者的MRC总评分,Meta分析结果显示:观察组MRC总评分高于对照组[MD=4.14,95%CI(2.69,5.58),P<0.01];6篇文献报道了患者住ICU期间的机械通气时间,Meta分析结果显示:观察组机械通气时间较对照组明显缩短[MD=-2.19,95%(-4.09,-0.30),P=0.02];5篇文献报道了患者的住ICU时间,Meta分析结果显示: 观察组住ICU时间较对照组明显缩短[MD=-1.80,95%CI(-3.33,-0.27),P=0.02]。结论:神经肌肉电刺激在ICU患者中应用是安全有效的,可提高MRC评分,缩短机械通气时间和住ICU时间,但仍需要多中心、大样本随机对照试验进一步证明。
英文摘要:
      Objective: To systematically review the effects of neuromuscular electrical stimulation (NMES) on muscle strength and clinical outcomes in ICU patients. Methods: Six databases including Cochrane Library, Web of Science, PubMed, CNKI, VIP and Wanfang database were searched for related literature from database established to December 2018. Randomized controlled trials (RCT) about the effects of NMES in ICU patients were collected. Literature screening, data extraction and quality evaluation were independently performed by two researchers. Meta-analysis was performed using RevMan software (version 5.3). Results: Fourteen studies were eventually included. The total MRC score of the patients was reported in 6 literature, and the Meta analysis results showed that the total MRC score in the observation group was significantly higher than that in the control group [MD=4.14, 95% CI (2.69, 5.58), P < 0.01]. Six literature reported the mechanical ventilation time of patients in ICU, and Meta analysis results showed that the mechanical ventilation time in the observation group was significantly shorter than in the control group [MD=-2.19, 95% CI (-4.09, -0.30), P=0.02]. The length of ICU stay in the observation group was significantly shorter than that in the control group [MD=-1.80, 95% CI (-3.33, -0.27), P=0.02]. Conclusion: The application of NMES in ICU patients is safe and effective. NMES can enhance MRC score, and shorten mechanical ventilation time and ICU stay. Also, Large sample and multi-center RCTs are needed to confirm the effects of NMES.
查看全文   下载PDF阅读器  HTML全文
关闭
本刊微信二维码