| 李菁,黄华垚,陈清法,陈振强.低频重复经颅磁刺激联合镜像疗法对脑梗死患者上肢运动功能恢复的临床研究[J].中国康复,2019,34(12):631-634 |
| 低频重复经颅磁刺激联合镜像疗法对脑梗死患者上肢运动功能恢复的临床研究 |
| Clinical study of low frequency repetitive transcranial magnetic stimulation combined with mirror therapy on the recovery of upper limbs’ motor functions in patients after cerebral infarction |
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| DOI： |
| 中文关键词: 重复经颅磁刺激 镜像疗法 脑梗死 上肢运动功能 |
| 英文关键词: Transcranial magnetic stimulation Mirror therapy Cerebral infarction Upper limb motor function |
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| 中文摘要: |
| 目的：探讨低频重复经颅磁刺激（rTMS）联合镜像疗法（MT）对脑梗死患者上肢运动功能恢复的影响。方法：60例脑梗死患者随机分为观察组和对照组各30例。2组患者均接受常规的临床药物治疗及规范的运动疗法和物理因子治疗。2组患者每天先进行rTMS治疗，观察组再进行MT治疗，对照组进行常规作业治疗。治疗前后采用简化Fugl-Meyer上肢运动功能评分(FMA)和上肢运动力指数(MI)评价患侧上肢运动功能，运动诱发电位(MEP)潜伏期和中枢运动传导时间(CMCT)指标进行神经电生理学评价。结果：治疗4周后，2组患者FMA和MI评分较治疗前均明显提高（均P<0.05），且观察组2项评分均明显高于对照组（均P<0.05）；2组患者 MEP潜伏期和CMCT均较治疗前缩短（均P<0.05），且观察组MEP潜伏期和CMCT均较对照组更短（均P<0.05）。结论：低频重复经颅磁刺激结合镜像疗法治疗能提高脑梗死患者的偏瘫上肢运动功能，且疗效优于低频重复经颅磁刺激结合常规作业疗法治疗。 |
| 英文摘要: |
| Objective: To explore the clinical effects of low-frequency repetitive transcranial magnetic stimulation (rTMS) combined with mirror therapy (MT) on the recovery of upper limbs’ motor functions in patients after cerebral infarction. Method: Sixty patients after cerebral infarction were randomly divided into two groups: the treatment group (n=30) and the control group (n=30). The patients of both groups all received standard medicine treatment and physical therapy. Patients in the treatment group and the control group were treated with low frequency rTMS every day, and then MT and routine operation were performed separately. Before and after treatment, the Fugl-Meyer motor assess (FMA) and Motricity index (MI) were used to evaluate the motor functions of the affected side, and neuroelectrophysiology was evaluated by motor envoked potential(MEP) incubation period and central motor conduction time(CMCT). Results: After 4 weeks of treatment, FMA and MI scores were significantly improved in both groups as compared with those before treatment (all P<0.05), and the scores in the teaetment group were significantly higher than those in the control group (all P<0.05). MEP latency and CMCT were significantly shorter after treatment in both groups than before treatment (all P<0.05), and MEP latency and CMCT were significantly shorter in the treatment group than in the control group (all P<0.05). Conclusion: Low-frequency rTMS combined with MT or conventional occupational therapy can both improve motor functions of hemiplegic upper limbs after cerebral infarction. And low-frequency rTMS combined with MT has better efficacy. |
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