| 张海林,葛海珏.呼吸功能康复训练对频繁急性加重哮喘-慢性阻塞性肺疾病重叠综合征患者的应用效果观察[J].中国康复,2020,35(6):312-316 |
| 呼吸功能康复训练对频繁急性加重哮喘-慢性阻塞性肺疾病重叠综合征患者的应用效果观察 |
| Clinical Efficacy of Respiratory Functional Rehabilitation Training in Patients with Frequent Acute Exacerbation ACOS |
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| DOI： |
| 中文关键词: 呼吸功能康复训练 频繁 急性加重 哮喘-慢性阻塞性肺疾病重叠综合征 |
| 英文关键词: respiratory functional rehabilitation training frequent acute exacerbation asthma-COPD overlap syndrome |
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| 中文摘要: |
| 目的：探讨呼吸功能康复训练在频繁急性加重哮喘-慢性阻塞性肺疾病重叠综合征（ACOS）患者中的应用效果。方法：将48例频繁急性加重的ACOS患者，随机分成对照组（n=24）和观察组（n=24）。对照组患者接受常规治疗和健康教育，观察组患者在对照组治疗基础上，同时在医护人员指导下进行呼吸功能康复训练治疗，训练周期为12周。测定治疗前后2组患者的呼吸频率、动脉血氧、肺功能、呼吸肌肌力、运动耐力、呼吸困难程度、生命质量和焦虑抑郁情绪等指标，并记录治疗前后2组1年内急性发作次数、住院次数和医疗费用，评价呼吸功能康复训练治疗的效果。结果：康复训练后，观察组呼吸频率、动脉血二氧化碳分压经治疗后均显著低于对照组，动脉血氧饱和度、动脉血氧分压均明显高于对照组（均P<0.05）；观察组治疗后肺功能各指标除了深吸气量其余均更高于对照组（均P<0.05）；治疗后，观察组6分钟步行距离明显高于对照组，而观察组治疗后的改良版呼吸困难量表评分和圣乔治呼吸问卷总分均明显低于对照组（均P<0.05）；治疗后观察组焦虑、抑郁评分和总分均明显低于对照组（均P<0.05）；观察组治疗后急性发作次数、住院次数和医疗费用均明显低于对照组（均P<0.05）。结论:呼吸功能康复训练能有效缓解急性加重ACOS患者的呼吸困难症状，增强呼吸肌肌力和运动耐力，改善抑郁、焦虑不良情绪，提高患者生活质量，同时降低了疾病复发率，减轻了患者经济负担。 |
| 英文摘要: |
| Objective: To explore the clinical efficacy of respiratory functional rehabilitation training in patients with frequent acute exacerbation asthma COPD overlap syndrome (ACOS). Methods: A total of 48 cases of frequent acute exacerbation ACOS were selected as the research subjects, and were divided into control group and observation group by random number table, 24 cases in each group. All patients in control group and observation were given normal therapy and healthy education, and those in observation group received respiratory functional rehabilitation training additionally, and the training time was 12 weeks. The parameters including respiratory rate (RR), arterial blood oxygen content, pulmonary function, respiratory muscle strength, exercise endurance, degree of dyspnea and quality of life, as well as anxiety and depression scores were measured before and 12 weeks after therapy, and the acute exacerbation frequency, times of hospitalization and medical cost within 1 year before and after the treatment were also recorded. All the clinical data were recorded to assess and compare the therapeutic effects of the two groups. Results: After 12 weeks of respiratory functional rehabilitation training, RR and PaCO2 in observation group were dramatically lower than those in control group (both P<0.05), while PaO2 and SaO2 were obviously higher than those in control group after training (both P<0.05). The pulmonary function indexes and the respiratory muscle strength indexes in observation group after training were significantly higher than those in control group except IC (all P<0.05). After training, 6 MWD in observation group was significantly increased as compared with that in control group, while mMRC and SGRQ total scores were significantly lower in observation group than those in control group after training (all P<0.05). The anxiety and depression scores and total scores in observation group were significantly lower than those in control group after training (all P<0.05). After training, the acute exacerbation frequency, times of hospitalization and medical cost within 1 year in observation group were dramatically reduced as compared with those in control group (all P<0.05). Conclusion: Respiratory functional rehabilitation training can effectively relieve the dyspnea symptoms in patients with frequent acute exacerbation ACOS, enhance respiratory muscle strength and exercise endurance, improve anxiety and depression emotion and the quality of life of patients, reduce the recurrence rate of ACOS, and lighten the economic burden on patients. |
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