文章摘要
高亚茹,关晨霞,李哲,郭钢花,乐琳,郝道剑.高频重复经颅磁刺激对认知障碍合并失语症脑卒中患者定向、视知觉及日常生活活动能力的影响[J].中国康复,2021,36(9):520-523
高频重复经颅磁刺激对认知障碍合并失语症脑卒中患者定向、视知觉及日常生活活动能力的影响
Effects of High-frequency Repetitive Transcranial Magnetic Stimulation on Orientation, Visual Perception and ADL of Stroke Patients with Cognitive Impairment and Aphasia
  
DOI:
中文关键词: 重复经颅磁刺激  脑卒中  认知功能障碍  失语症  定向及视知觉  日常生活活动能力
英文关键词: repetitive transcranial magnetic stimulation  stroke  cognitive impairment  aphasia  orientation and visual perception  ability of daily living
基金项目:河南省科技发展计划项目基金资助(192102310313)
作者单位
高亚茹 郑州大学第五附属医院康复医学科郑州 450000 
关晨霞 郑州大学第五附属医院康复医学科郑州 450000 
李哲 郑州大学第五附属医院康复医学科郑州 450000 
郭钢花 郑州大学第五附属医院康复医学科郑州 450000 
乐琳 郑州大学第五附属医院康复医学科郑州 450000 
郝道剑 郑州大学第五附属医院康复医学科郑州 450000 
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中文摘要:
  目的:探讨高频(10Hz)重复经颅磁刺激(rTMS)对同时伴有认知障碍、失语症的脑卒中患者定向、视知觉及日常生活活动能力(ADL)的疗效。方法:50例脑卒中患者随机分成观察组和对照组各25例,2组患者均接受常规药物治疗及康复训练(认知、言语功能训练等),观察组于左侧前额叶背外侧皮质加以10Hz的rTMS治疗,对照组接受空白rTMS。治疗前和治疗4周后选用洛文斯顿作业疗法认知量表(Lotca)中定向和视知觉,改良Barthel指数(MBI)及事件相关电位P300对2组患者进行评定。结果:治疗4周后,2组Lotca定向、视知觉及MBI评分较治疗前均显著增加(均P<0.01),且观察组以上评分均明显高于对照组(均P<0.05);2组P300的潜伏期均较治疗前显著缩短(均P<0.01),波幅较治疗前均显著增大(均P<0.01),且观察组P300的潜伏期较对照组更短(P<0.01),波幅较对照组更高(P<0.01)。结论:高频rTMS治疗能有效促进认知障碍合并失语症脑卒中患者定向、视知觉及ADL能力的恢复。
英文摘要:
  Objective: To explore the effects of 10 Hz repetitive transcranial magnetic stimulation (rTMS) on the rehabilitation of orientation, visual perception and ability of daily living (ADL) in stroke patients with cognitive impairment and aphasia. Methods: Totally, 50 stroke patients were divided into treatment group (n=25) and control group (n=25) according to the random principle. Both groups were given conventional medication and cognitive and speech rehabilitation training. The treatment group accepted 10 Hz rTMS. The control group received sham stimulation. Before and after treatment for 4 weeks, orientation and visual perception in the Lowenston Occupational Therapy Cognitive Scale (Lotca), modified Barthel index (MBI), and event-related potential P300 were used to evaluate the two groups. Results: After 4 weeks of treatment, orientation and visual perception in Lotca scale and MBI scores of the two groups were significantly higher than those before treatment (all P<0.01), and the scores of the treatment group were significantly higher than those of the control group (all P<0.05). The latency of P300 in both groups was significantly shortened (all P<0.01) and the amplitude of P300 in both groups was significantly increased (all P<0.01). The latency of P300 was shorter (P<0.01) and the amplitude was higher in treatment group than those in control group (P<0.01). Conclusion: High-frequency rTMS treatment can effectively promote the recovery of orientation and visual perception and ADL in patients with cognitive impairment and aphasia.
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