| 钟毓贤,刘峰,任贺,丁宇,马广昊,杜薇,潘灵芝,陈婷婷,马俪维,付本升.超声引导下针刀联合富血小板血浆注射技术治疗膝关节骨性关节炎的临床疗效观察[J].中国康复,2022,37(2):95-100 |
| 超声引导下针刀联合富血小板血浆注射技术治疗膝关节骨性关节炎的临床疗效观察 |
| Therapeutic effects of ultrasound-guided acupotomy combined with platelet-rich plasma on knee osteoarthritis |
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| DOI： |
| 中文关键词: 针刀 超声 膝关节骨性关节炎 富血小板血浆 |
| 英文关键词: Acupotomy Ultrasound-guided Knee osteoarthritis Platelet-rich plasma |
| 基金项目:军队后勤科研计划重点项目（BHJ17J010）；中国人民解放军总医院第六学中心创新培育基金（CXPY201917）；训练伤防治专项（21XL535） |
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| 中文摘要: |
| 目的: 研究利用超声引导下针刀联合富血小板血浆（PRP）注射技术治疗膝关节骨性关节炎(KOA)，并通过客观步态分析来评估患者的步行活动能力，以期实现KOA精准、科学、有效的综合治疗手段。方法：72例KOA患者分为观察组和对照组各36例，观察组为超声引导下针刀联合关节腔内注射PRP治疗方法，对照组采用常规的关节腔内注射透明质酸钠、关节腔外痛点注射封闭方法，利用临床愈显率、疼痛视觉模拟评定(VAS)、Lysholm膝关节评分和步行绝对对称指数（ASI）评价两种治疗方法的临床疗效。结果：治疗3个月后，观察组临床愈显率明显高于对照组（86.11%、27.78%，P<0.01）；观察组的VAS评分和Lysholm膝关节评分均优于对照组（均P<0.01）；观察组患者的步频、步速、步幅、承重期膝屈曲角度的ASI也明显优于对照组（均P<0.05）。结论：超声引导下针刀联合PRP注射技术不但可以实现针刀及PRP注射的可视化、精准化治疗，更能够实现对KOA关节内外的全面干预，从而改善患者膝关节活动能力和步行稳定性。 |
| 英文摘要: |
| Objective: To study the therapeutic effects of ultrasound-guided acupotomy combined with platelet-rich plasma (PRP) on knee osteoarthritis (KOA). Methods: A total of 72 patients with KOA were divided into observation group (36 cases) and control group (36 cases). Patients in the observation group received treatment of ultrasound-guided acupotomy combined with PRP, and those in the control group received intra articular injection of sodium hyaluronate and local blocking. The effects of the two groups were evaluated with effective rate, visual analogue score (VAS), Lysholm knee score and absolute symmetry index (ASI). Results: After 3 months, the markedly effective rate in the observation group and control group was 86.11% and 27.78% respectively, and the difference was significant (P<0.01). Meanwhile, VAS (2.50±0.34 vs. 4.05±0.39) and Lysholm knee score (85.03±3.25 vs. 79.28±3.42) in the observation group were better than those in the control group (all P<0.01). There were significant differences in the ASIs between the observation group and control group ［stride frequency: (2.04±0.34 vs. 4.24±0.46); pace: (4.09±0.62 vs. 7.64±1.18); stride length: (4.67±0.41 vs. 6.36±0.57); and knee flexion angle: (5.21±1.06 vs. 7.38±1.19) (all P<0.05)］. Conclusion: Ultrasound-guided acupotomy combined with PRP injection can not only achieve the visualization and precision of acupotomy and PRP injection, but also realize the comprehensive intervention inside and outside the joint, and it can eventually improve the mobility of knee joint and walking stability of patients with KOA. |
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