| 成贵卿,孙晓龙,孙妙巧,徐沐兰,吴相波,梁英,戴春秋,王虹,李宁,牛丹,张艳荣,袁华.影响脊髓损伤患者预后的营养相关独立危险因素分析[J].中国康复,2023,38(5):286-290 |
| 影响脊髓损伤患者预后的营养相关独立危险因素分析 |
| Independent nutritional risk factors for functional prog nosis of patients with spinal cord injury |
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| DOI： |
| 中文关键词: 脊髓损伤 营养不良 预后 低血红蛋白 低血尿素氮 |
| 英文关键词: spinal cord injury malnutrition prognosis low hemoglobin low blood urea nitrogen |
| 基金项目:国家自然科学基金(82072534,82272591)；陕西省自然科学基础研究计划项目(2019JQ-043) |
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| 中文摘要: |
| 目的：本研究探讨入院时临床营养指标对脊髓损伤患者功能预后的影响。方法：回顾性分析2018年1月～2022年7月于空军军医大学第一附属医院康复医学科住院的195例脊髓损伤患者的病例资料，按照改良Barthel指数的平均相对功能恢复百分比（mRFG）分为mRFG≤0.5组和mRFG>0.5组。分别比较入院时2组患者的一般情况、住院时长、损伤节段、ASIA分级、受伤时间、合并症、营养相关实验室检查等指标。采用多因素logistic回归分析筛选影响整体功能预后的营养因素。结果：195例脊髓损伤患者中有154例mRFG≤0.5。多因素logistic回归分析结果显示，脊髓损伤患者mRFG≤0.5和低血红蛋白（OR=2.324，P=0.049）、低血尿素氮（OR=4.569，P=0.047）、教育程度（高中及以下，OR=3.173，P=0.015）有关。结论：低血红蛋白、低血尿素氮是影响脊髓损伤患者整体功能预后相关的独立营养危险因素。脊髓损伤住院患者入院时，应重点关注血红蛋白、血尿素氮等营养指标。对于低血红蛋白及低血尿素氮的患者应及时予以纠正，可能有助于进一步改善脊髓损伤患者的康复效果。 |
| 英文摘要: |
| Objective: To investigate the clinical nutritional indicators at admission affecting the functional prognosis of patients with spinal cord injury (SCI). Methods：The medical records of 195 patients with SCI who were hospitalized in the Department of Rehabilitation Medicine of the First Affiliated Hospital of Air Force Military Medical University from January 2018 to July 2022 were retrospectively analyzed. According to the mean relative function gain (mRFG) of the modified Barthel index, the patients were divided into mRFG ≤0.5 (bad prognosis) group and mRFG >0.5 (good prognosis) group. The basic conditions, length of hospital stay, injury level, ASIA classification, injury time, complications and nutrition-related laboratory tests were compared between the two groups at admission. Multivariate logistic regression analysis was used to screen out the risk factors of SCI. Results：Totally, 154 out of 195 SCI patients obtained mRFG ≤0.5. After the multivariate logistic regression analysis, low hemoglobin (OR=2.324, P=0.049), low blood urea nitrogen (OR=4.569, P=0.047) and low educational levels (senior high school and below, OR=3.173, P=0.015) were significantly associated with mRFG ≤0.5. Conclusion：Low hemoglobin and low blood urea nitrogen are independent risk factors for patients with SCI. The hemoglobin and blood urea should be focused on in the patients with SCI at admission. The low hemoglobin and low blood urea nitrogen should be corrected in time, which may help to improve the rehabilitation effect of SCI patients. |
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