| 司徒功瑶,孙洁,张莉,唐艳,高思宇,宁博.重复经颅磁刺激应用于脑卒中后认知并摄食障碍患者的疗效观察[J].中国康复,2023,38(11):649-653 |
| 重复经颅磁刺激应用于脑卒中后认知并摄食障碍患者的疗效观察 |
| Efficacy of repetitive transcranial magnetic stimulation for cognitive and ingestion disorders in stroke patients |
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| DOI： |
| 中文关键词: 脑卒中 认知障碍 摄食障碍 重复经颅磁刺激 |
| 英文关键词: stroke cognitive impairment ingestion disorder rTMS |
| 基金项目:江苏省科技项目（BE2020638）；徐州市医学领军人才培养项目（XWRCHT20210024）；江苏省老年健康科研项目（LKM2022046） |
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| 中文摘要: |
| 目的：观察重复经颅磁刺激（rTMS）对脑卒中后认知并摄食障碍患者的认知及摄食功能的疗效。方法：将60例脑卒中后具有认知障碍和摄食障碍的患者随机分为对照组和观察组各30例。2组患者均给予常规药物治疗、常规认知训练及常规摄食训练，观察组另外行rTMS治疗，疗程共4周。于治疗4周前后评估患者认知及摄食功能变化情况。结果：治疗4周后，2组患者简易精神状态量表（MMSE）评分、24h摄入量均较治疗前显著提高（P＜0.01），荧光透视吞咽困难量表（VDS）评分、口腔转运时间（OTT）及软腭上抬时间（SET）数值均较前治疗前显著缩短（P＜0.01）；治疗4周后，观察组MMSE评分、24h摄入量均较对照组升高（P＜0.01），VDS评分、OTT及SET数值较对照组缩短（P＜0.01）。观察组治疗后MMSE评分与24h摄入量呈显著正相关（rs=0.757，P＜0.01），MMSE评分与VDS评分呈负相关（rs=-0.432，P＜0.05），MMSE评分与OTT数值呈负相关（rs=-0.422，P＜0.05），MMSE评分与SET数值呈负相关（rs=-0.430，P＜0.05）。结论：rTMS治疗能有效改善脑卒中后认知并摄食障碍患者的认知及摄食功能。 |
| 英文摘要: |
| Objective: To observe the efficacy of repetitive transcranial magnetic stimulation (rTMS) for cognitive and ingestion disorders in stroke patients. Methods: A total of 60 patients with cognitive and ingestion disorders after stroke were randomly assigned into control group (n=30) and observation group (n=30). All patients in both groups were given conventional drug therapy. The control group received routine cognitive training and ingestion training. The observation group received rTMS on the basis of the control group. After treatment for 4 weeks, the cognition and ingestion of the two groups were evaluated and analyzed respectively. Results: The score of Mini-mental state examination (MMSE), the 24-h intake, the score of video fluoroscopic dysphagia scale (VDS), the oral transit time (OTT) and the soft palate elevation time (SET) were significantly improved after treatment in both groups (P<0.01), and those in the observation group were better than in the control group (P<0.01). In the observation group, the MMSE score was significantly and positively related with 24-h intake (rs=0.757, P<0.01), the MMSE score was negatively related with VDS score (rs=-0.432, P<0.05), the MMSE score was negatively related with OTT (rs=-0.422, P<0.05), and the MMSE score was negatively related with SET (rs=-0.430, P<0.05). Conclusion: rTMS can effectively improve the cognitive and ingestion functions in patients with cognitive impairment and ingestion disorders after stroke. |
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