| 游煌俊,刘冲冲,孙伟铭,陈招君,帅浪.吸气肌训练对支气管哮喘患者肺功能影响的Meta分析[J].中国康复,2024,39(2):105-110 |
| 吸气肌训练对支气管哮喘患者肺功能影响的Meta分析 |
| Effect of inspiratory muscle training on pulmonary function of patients with asthma: a meta-analysis |
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| DOI： |
| 中文关键词: 吸气肌训练 支气管哮喘 肺功能 荟萃分析 |
| 英文关键词: inspiratory muscle training asthma pulmonary function meta-analysis |
| 基金项目:江西省03专项及5G项目（20224ABC03A04）；江西省重点研发计划项目（20202BBE53021）；江西省中医药管理局科技计划项目（2021B150）；江西省卫生健康委科技计划（202210464）；江西省中医药管理局科技计划项目（2020A0058） |
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| 中文摘要: |
| 目的：系统评价吸气肌训练对支气管哮喘（哮喘）患者肺功能的影响。方法：计算机检索PubMed、Cochrane Library、EMBASE、中国知网（CNKI）、万方数据知识服务平台（Wanfang Data）、维普网（VIP）等数据库，查找自建库至2023年7月关于吸气肌训练对哮喘患者肺功能影响的随机对照试验。两名研究人员独立筛选文献、提取资料，按照Cochrane手册评价纳入文献的偏倚风险，然后采用RevMan 5.3软件进行Meta分析。结果：共纳入7篇文献，包括229例受试者。Meta分析结果显示：与对照组相比，吸气肌训练能有效地改善用力肺活量占预计值百分比［MD=10.86，95%CI(4.34，17.38)，P=0.001］、呼气峰流速［MD=98.47，95%CI(71.76，125.19)，P<0.00001］、和最大呼气压［MD=21.67，95%CI(5.50，37.85)，P=0.0009］，但对第一秒用力呼气容积占预计值百分比 ［MD=4.51，95%CI(-3.55，12.56)，P=0.27］、一秒率［MD=-2.70，95%CI(-18.71，13.30)，P=0.74］的改善情况与对照组相比，差异无统计学意义。干预时长大于8周的吸气肌训练组最大吸气压显著高于对照组［MD=16.25，95%CI(5.62，26.88)，P=0.003］；干预时长小于8周，2组间差异无统计学意义［MD=36.51，95%CI(-0.62，73.64)，P=0.05］。结论：吸气肌训练能有效改善哮喘患者的呼吸肌肌力，且对肺通气功能部分指标有明显提高。 |
| 英文摘要: |
| Objective： To systematically evaluate the effect of inspiratory muscle training on lung function in patients with bronchial asthma (asthma). Methods： PubMed, Cochrane Library, EMBASE, CNKI, Wanfang Data, VIP and other databases were searched for the randomized controlled trials (RCT) about inspiratory muscle training on pulmonary function of patients with asthma from inception to July 2023. Two researchers independently screened the literature, extracted data, evaluated the risk of bias of the included literature according to the Cochrane Handbook, and then performed Meta-analysis using RevMan 5.3 software. Results： A total of 7 literatures were included, including 229 subjects. The results of meta-analysis showed that, compared with the control group, inspiratory muscle training effectively improved forced vital capacity of predicted value (MD=10.86, 95%CI 4.34 to 17.38, P=0.001), peak expiratory flow (MD=98.47, 95%CI 71.76 to 125.19, P<0.00001), maximal inspiratory pressure (MD=26.21, 95%CI 1.71 to 50.72, P=0.04) and maximal expiratory pressure (MD=21.67, 95%CI 5.50 to 37.85, P=0.0009). There were significant differences between two groups. Conclusion： Inspiratory muscle training can effectively improve the strength of respiratory muscles in patients with asthma, and can significantly improve some indexes of pulmonary ventilation function. |
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