| 王莉,蒋惠瑜,吴秀香,朱毅.味觉刺激对吞咽功能的影响[J].中国康复,2025,40(6):373-378 |
| 味觉刺激对吞咽功能的影响 |
| Effect of taste stimulation on swallowing function |
| |
| DOI：10.3870/zgkf.2025.06.009 |
| 中文关键词: 味觉刺激 吞咽功能 |
| 英文关键词: taste stimulation swallowing function |
| 基金项目:海南省自然科学基金项目（NO.820QN402） |
|
| 摘要点击次数: 265 |
| 全文下载次数: 138 |
| 中文摘要: |
| 目前国际上已初步开展通过各种感觉刺激改善动物和人类吞咽功能的研究。其中作为重要感觉刺激手段之一的味觉刺激，我国缺乏详尽报道和相关研究。本文旨在综述味觉刺激对吞咽功能的影响，综述味觉刺激对吞咽功能的影响和临床研究进展，以期为吞咽障碍的康复提供新策略及参考依据。纳入2025年2月前公开发表的国内外味觉刺激对吞咽功能影响的相关文献，综述相关内容。口咽部感觉输入对于吞咽运动序列的启动和调节非常重要。包括味觉刺激在内的外周感觉刺激策略在人类和动物研究中被逐渐开发应用。味觉刺激激活的多个脑区是与吞咽网络重叠的关键脑区，如岛叶、眶额皮层、杏仁核、扣带回、前中央回、后中央回、小脑等。味觉刺激对吞咽的影响受年龄、认知、遗传味觉状态（GTS）、唾液等因素影响。五种纯味觉刺激中，浓酸刺激对吞咽功能的影响效果最好,包括更快更强的吞咽肌肉激活、延长呼吸暂停持续时间、减少气道误吸、增加吞咽频率等。其他四种甜、咸、苦、咸味觉刺激和复杂口味刺激多集中在健康人群中研究，也被初步证实对吞咽有一定积极影响。但总体证据尚存在一定局限性，还需更多随机、对照、多中心试验来更进一步研究确切的有效剂量、浓度、刺激时间、影响疗效的变量等。大部分证据支持味觉刺激可对吞咽功能产生不同程度的有利影响，其显示出良好的临床应用价值和潜力，值得更进一步深入探索和应用。 |
| 英文摘要: |
| Preliminary international research has been conducted to improve swallowing function in animals and humans through various sensory stimuli.Among them, as one of the important sensory stimulation means of taste stimulation, there is a lack of detailed reports and related research in our country.The purpose of this paper is to review the effects of taste stimulation on swallowing function. To review the effects of taste stimulation on swallowing function and the progress of clinical research, aiming to providing new strategies and reference for the rehabilitation of swallowing disorders. We included and reviewed articles published before February 2025 on the effects of taste stimulation on swallowing function. Oropharyngeal sensory inputs were important for the initiation and regulation of swallowing motor sequences. Peripheral sensory stimulation strategies, including taste stimulation, have been progressively developed and applied in human and animal studies. Several brain regions activated by taste stimulation were key brain regions overlapping with the swallowing network, such as insula, orbitofrontal cortex, amygdala, cingulate gyrus, anterior central gyrus, posterior central gyrus, and cerebellum. The effect of taste stimuli on swallowing was influenced by age, cognition, genetic taste status (GTS), and saliva. Of the five purely taste stimuli, concentrated acidic stimuli had the best effects on swallowing function, including faster and stronger swallowing muscle activation, prolongation of apnea duration, reduction of airway malabsorption, and increased swallowing frequency. The other four sweet, salty, bitter and savory taste stimuli and complex taste stimuli have been studied in healthy populations and have also been preliminarily shown to have a positive effect on swallowing. However, the overall evidence was limited, and more randomized, controlled, multicenter trials are needed to more closely examine the exact effective dose, concentration, duration of stimulation, and variables affecting efficacy. Most of the evidence supports that gustatory stimulation can have different degrees of favorable effects on swallowing function, and it shows good clinical value and potential, which is worthy of further in-depth exploration and application. |
|
查看全文
下载PDF阅读器 HTML全文 |
| 关闭 |
|
|
|
