| 冯畑,王熠钊,赵洁玮,向世强.古琴音乐联合重复经颅磁刺激治疗脑卒中后抑郁的效果观察[J].中国康复,2025,40(7):418-421 |
| 古琴音乐联合重复经颅磁刺激治疗脑卒中后抑郁的效果观察 |
| Guqin music therapy combined with repetitive transcranial magnetic stimulation for post-stroke depression |
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| DOI：10.3870/zgkf.2025.07.007 |
| 中文关键词: 脑卒中后抑郁 古琴音乐治疗 重复经颅磁刺激 非药物治疗 |
| 英文关键词: post-stroke depression Guqin music therapy repetitive transcranial magnetic stimulation non-pharmacological treatments |
| 基金项目:湖北本科高校省级教学改革研究项目（2023193） |
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| 中文摘要: |
| 目的：探讨古琴音乐联合重复经颅磁刺激（rTMS）对脑卒中后抑郁患者的干预效果。方法：将70例脑卒中后抑郁患者，随机分为观察组、对照组各35例。2组均接受常规康复治疗和10Hz rTMS治疗，观察组在此基础上增加古琴音乐治疗，均治疗6周。2组在研究过程中分别脱落2例、1例，最终纳入33例、34例。2组分别在治疗前及治疗6周后使用汉密尔顿抑郁量表-24（HAMD-24）、美国国立卫生研究院卒中量表(NIHSS)评估患者的抑郁状态和神经功能缺损程度。结果：治疗6周后，2组HAMD评分及其中的阻滞因子、躯体性焦虑因子、睡眠障碍因子评分、NIHSS评分均较治疗前降低（P<0.01），且观察组上述指标低于对照组（P<0.01）；2组疗效比较显示，观察组总有效率高于对照组（P<0.01）。结论：古琴音乐治疗联合rTMS对脑卒中后抑郁患者的干预效果优于单独rTMS治疗，可作为安全有效的辅助治疗方法。 |
| 英文摘要: |
| Objective: To investigate the therapeutic effect of combining Guqin music therapy with repetitive transcranial magnetic stimulation (rTMS) for patients with post-stroke depression. Methods: A total of 70 patients diagnosed with post-stroke depression were randomly assigned to either an experimental group or a control group. Both groups received standard rehabilitation treatments along with rTMS (target site: left dorsolateral prefrontal cortex; frequency: 10 Hz; intensity: 80%-120% motor threshold; duration: 20 min per session; frequency: once daily, 5 times weekly for 6 weeks). Additionally, the experimental group underwent Guqin music therapy (listening to 15 classical pieces of Guqin music for 30 min each session, once daily, 5 times weekly for 6 weeks). During the study period, one and two patients in the experimental group and the control group withdrew from the study at different stages, resulting in a final sample size of 33 patients in the experimental group and 34 patients in the control group.The Hamilton depression scale (HAMD-24) was utilized to assess the depressive symptoms of patients before and after the intervention of 6 weeks. The National Institutes of Health stroke scale (NIHSS) was used to evaluate the degree of neurological deficit. Results: Post-treatment HAMD scores and NIHSS scores for both groups were significantly reduced compared to baseline levels (P<0.01). The block factor, somatic anxiety factor, and sleep disorder factor scores showed significant reductions post-intervention (P<0.01), with the experimental group demonstrating more pronounced improvements relative to the control group. The total effective rate in the experimental group was higher than in the control group. Conclusion: Guqin music therapy combined with rTMS demonstrates a significantly superior effect on post-stroke depression compared to rTMS alone, suggesting its potential as a safe and effective adjunctive treatment. |
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