| 谢冰,陈丹,倪伟,刘秋红,肖乐,刘超,李元.末端牵引式上肢机器人联合间歇性θ短阵脉冲刺激治疗对脑卒中上肢功能障碍的疗效研究[J].中国康复,2025,40(8):458-462 |
| 末端牵引式上肢机器人联合间歇性θ短阵脉冲刺激治疗对脑卒中上肢功能障碍的疗效研究 |
| Efficacy of end-effector upper limb robot combined with iTBS on upper limb dysfunction in stroke patients |
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| DOI：10.3870/zgkf.2025.08.002 |
| 中文关键词: 脑卒中 上肢功能障碍 上肢机器人 间歇性θ短阵脉冲刺激 |
| 英文关键词: stroke upper limb dysfunction upper limb robot iTBS |
| 基金项目:湖南省自然科学基金医卫联合项目（2025JJ80497）；湖南省卫生健康委一般指导项目（D202319016981） |
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| 中文摘要: |
| 目的：本研究旨在探讨末端牵引式上肢机器人联合间歇性θ短阵脉冲刺激（iTBS）治疗对脑卒中上肢功能障碍的临床康复效果。方法：将60例脑卒中上肢功能障碍患者随机分成对照组与观察组，2组均接受常规康复训练，对照组在此基础上给予iTBS治疗，观察组在对照组基础上联合末端牵引式上肢机器人治疗，治疗时间为持续4周。比较治疗前后2组患者Fugl-Meyer上肢运动功能量表（FMA-UE）、手臂动作调查测试（ARAT）、改良Barthel指数（MBI）、患侧大脑运动诱发电位(MEP)波幅、潜伏期。结果：治疗后2组的FMA-UE、ARAT、MBI评分较治疗前均提高（P＜0.01），且观察组评分高于对照组（P＜0.01）。治疗后2组患者患侧大脑MEP波幅较治疗前均增大、潜伏期较治疗前缩短(P<0.01),且观察组变化程度大于对照组(P<0.01)。结论：末端牵引式上肢机器人联合iTBS治疗能有效改善脑卒中患者上肢运动功能及日常生活活动能力，提高MEP波幅，缩短潜伏期，提高临床效果，值得临床推广和应用。 |
| 英文摘要: |
| Objective: To investigate the clinical rehabilitation effect of end-effector upper limb robot combined with iTBS on upper limb dysfunction in stroke patients. Methods: A total of 60 stroke patients were assigned to a control group and an observation group. Both groups received conventional rehabilitation training. The control group was given iTBS treatment on this basis, while the observation group was given end-effector upper limb robot combined with iTBS. The treatment lasted for 4 weeks. The Fugl-Meyer Assessment of Upper Extremity (FMA-UE), Action Research Arm Test (ARAT), Modified Barthel Index (MBI), amplitude and latency of motor evoked potential (MEP) on the affected hemisphere were compared before and after treatment in both groups. Results: Compared with before treatment, the FMA-UE, ARAT, and MBI scores of both groups after treatment were increased, and the differences were statistically significant (P<0.01). After treatment, the FMA-UE, ARAT, and MBI scores in the observation group were significantly higher than in the control group (P<0.01). After treatment, the amplitude of MEP on the affected hemisphere increased and the latency decreased in both groups as compared with that before treatment (P<0.01), and that in the observation group was significantly greater than in the control group (P<0.01). Conclusion: End-effector upper limb robot combined with iTBS can effectively improve the upper limb motor function and activities of daily living ability of stroke patients, increase the amplitude of MEP, shorten the latency and improve the clinical effect. It is worthy of clinical promotion and application. |
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