| 张洪宇,方伯言.经颅交流电刺激技术在神经康复中的研究进展[J].中国康复,2025,40(10):624-629 |
| 经颅交流电刺激技术在神经康复中的研究进展 |
| Research progress on transcranial alternating current stimulation in neurorehabilitation |
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| DOI：10.3870/zgkf.2025.10.008 |
| 中文关键词: 经颅交流电刺激 神经振荡 神经康复 脑卒中 帕金森病 |
| 英文关键词: transcranial alternating current stimulation neural oscillations neurorehabilitation stroke Parkinson’s disease |
| 基金项目:国家重点研发计划项目（2022YFC3602603）；北京市石景山区医学重点学科科研项目（2023002） |
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| 中文摘要: |
| 经颅交流电刺激（tACS）作为一种新兴的非侵入性脑刺激技术，通过外源节律性正弦电流影响神经振荡，调节神经网络功能与可塑性。近年来，tACS在神经康复中的研究逐渐增多，显示其在运动、感觉、认知和情绪等功能障碍的应用潜力。本文综述tACS的作用机制及其在神经系统疾病如脑卒中、帕金森病等疾病中的应用价值。现有的研究表明tACS可通过调节神经振荡、促进突触可塑性、同步脑网络活动和影响神经递质，改善神经功能，在多种疾病康复中显示良好效果。tACS为神经康复提供新手段，具有广阔应用前景。未来应优化个体化参数，推动其临床转化应用。 |
| 英文摘要: |
| Transcranial alternating current stimulation (tACS) is a novel non-invasive brain stimulation technique that influences neural oscillations and modulates brain network function and plasticity through external rhythmic sine-wave currents. In recent years, research on tACS in neurorehabilitation has increased, showing its potential in motor, sensory, cognitive, and emotional dysfunction. This study systematically reviewed the mechanisms of tACS and its application in neurorehabilitation, and to evaluate its value in diseases such as stroke and Parkinson’s disease. tACS can regulate neural oscillations, promote synaptic plasticity, synchronize brain network activity, and affect neurotransmitters, improving neural function and showing good effects in rehabilitation of various diseases. tACS provides a new approach for neurorehabilitation with broad application prospects. Future studies should optimize individualized parameters and promote clinical translation. |
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