| 王庆雷,阚超杰,朱仕哲,耿阿燕,沈俊帆,王彤,郭川.小脑重复经颅磁刺激在神经系统疾病下肢运动障碍中的研究进展[J].中国康复,2025,40(12):754-759 |
| 小脑重复经颅磁刺激在神经系统疾病下肢运动障碍中的研究进展 |
| Research progress of repetitive transcranial magnetic stimulation of the cerebellum in lower limb motor disorders of neurological diseases |
| |
| DOI：10.3870/zgkf.2025.12.009 |
| 中文关键词: 经颅磁刺激 小脑 神经系统疾病 运动障碍 |
| 英文关键词: transcranial magnetic stimulation cerebellum neurological diseases movement disorders |
| 基金项目:国家自然科学基金青年项目（82302882） |
|
| 摘要点击次数: 120 |
| 全文下载次数: 55 |
| 中文摘要: |
| 各类神经系统疾病导致的下肢运动障碍往往会严重影响患者的日常生活质量，而重复经颅磁刺激通过调节神经的兴奋性能够改善神经受损导致的运动障碍，其中小脑靶点因其在平衡功能中发挥重要作用受到了越来越多的关注。然而目前研究中所采用的刺激方案尚不统一，疗效尚不确切。因此本研究综述了小脑重复经颅磁刺激在不同神经系统疾病的相关研究，发现其在脑卒中、脊髓小脑共济失调、帕金森病以及其他神经系统疾病中显示出不同程度的临床疗效，其主要通过改善小脑内血流和代谢以及调节小脑-丘脑-皮质回路来改善患者的下肢运动功能障碍，这为小脑重复经颅磁刺激的临床应用提供了更多的参考与理论依据。 |
| 英文摘要: |
| Lower limb motor dysfunction caused by various neurological diseases often severely impacts patients’ quality of daily life. Repetitive transcranial magnetic stimulation (rTMS) can ameliorate motor impairments resulting from neural damage by modulating neural excitability. Among the stimulation targets, the cerebellum has garnered increasing attention due to its crucial role in balance function. However, the stimulation protocols used in current studies are not yet standardized, and the therapeutic efficacy remains uncertain. Therefore, this review summarizes research on cerebellar rTMS in various neurological disorders. The findings indicate that cerebellar rTMS demonstrates varying degrees of clinical effectiveness in stroke, spinocerebellar ataxia, Parkinson’s disease, and other neurological conditions. It primarily improves lower limb motor dysfunction by enhancing cerebellar blood flow and metabolism, as well as modulating the cerebellar-thalamo-cortical circuit. This provides additional references and a theoretical basis for the clinical application of cerebellar rTMS. |
|
查看全文
下载PDF阅读器 HTML全文 |
| 关闭 |
