| 张军玲,潘海英,李晓云,刘海,冯海丽,郭洁.经颅直流电刺激联合认知-运动双重任务训练对脑卒中后认知功能障碍的疗效观察[J].中国康复,2026,41(2):73-77 |
| 经颅直流电刺激联合认知-运动双重任务训练对脑卒中后认知功能障碍的疗效观察 |
| Influence of transcranial direct current stimulation combined with cognitive-motor dual task training on patients with post-stroke cognitive impairment |
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| DOI：10.3870/zgkf.2026.02.002 |
| 中文关键词: 经颅直流电刺激 认知-运动双重任务训练 脑卒中后认知功能障碍 疗效 |
| 英文关键词: transcranial direct current stimulation cognitive-motor dual task training post-stroke cognitive impairment curative effect |
| 基金项目:潍坊市科技发展计划项目（2024YX114） |
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| 中文摘要: |
| 目的：观察经颅直流电刺激（tDCS）联合认知-运动双重任务（CMDT）训练治疗脑卒中后认知功能障碍（PSCI）的疗效。方法：选择2023年9月至2024年9月我院收治的PSCI患者124例，按随机数字表法分为对照组和研究组各62例，分别给予CMDT和经颅直流电刺激（tDCS）联合CMDT治疗。比较2组患者治疗前后认知功能、运动功能、日常生活活动能力、平衡功能及血清神经递质浓度的变化。结果：治疗后，2组简易智能精神状态检查量表（MMSE）评分、蒙特利尔认知评估量表（MoCA）评分、Fugl-Meyer运动功能评分量表上肢部分（FMA-UE）、Fugl-Meyer运动功能评分量表下肢部分（FMA-LE）评分、改良巴氏指数（MBI）评分、Berg平衡量表（BBS）评分均高于治疗前（均P＜0.01），且研究组均高于对照组（均P＜0.01）。治疗后，2组血清多巴胺、血浆去甲肾上腺素（NE）浓度均高于治疗前，且研究组高于对照组（均P＜0.01）。结论：与单纯CMDT相比，tDCS联合CMDT能更显著地改善PSCI患者的认知功能、运动功能、日常生活活动能力和平衡功能，患者血清递质多巴胺、NE水平升高。 |
| 英文摘要: |
| Objective: To observe the curative effect of transcranial direct current stimulation (tDCS) in combination with cognitive-motor dual task (CMDT) training in treating post-stroke cognitive impairment (PSCI). Methods: From September 2023 to September 2024, 124 PSCI patients who visited our hospital were randomly allocated into the control group (n=62, given CMDT training) and the study group (n=62, given tDCS + CMDT training) via random number table method. The neurotransmitters, cognitive status, motor function, modified Barthel index (MBI) score, and Berg Balance Scale (BBS) score were compared between the two groups before and after the treatment. Results: After the treatment, the plasma dopamine concentration, plasma norepinephrine (NE) concentration, Mini Mental State Examination (MMSE) score, Montreal Cognitive Assessment (MoCA) score, Fugl-Meyer Assessment (FMA)-Upper Limb score, FMA-Lower Limb score, MBI score, and BBS score in both groups were higher than those before the treatment (P<0.05), and the scores in the study group were higher than those in the control group (P<0.05). Conclusion: Compared with simple CMDT training, tDCS combined with CMDT training can significantly improve the cognitive function, motor function, daily living activity ability and balance function of patients with PSCI. The mechanism of its effect may be related to the regulation of dopamine and norepinephrine levels. |
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