| 刘志伟,孙晓,王建华,张娜妍.经颅磁刺激联合贴扎技术治疗缺血性脑卒中患者运动功能障碍的效果观察[J].中国康复,2026,41(3):146-151 |
| 经颅磁刺激联合贴扎技术治疗缺血性脑卒中患者运动功能障碍的效果观察 |
| Transcranial magnetic stimulation combined with patch technique for the treatment of motor dysfunction in ischemic stroke |
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| DOI：10.3870/zgkf.2026.03.004 |
| 中文关键词: 经颅磁刺激 贴扎技术 缺血性脑卒中 运动功能 |
| 英文关键词: transcranial magnetic stimulation patch technique ischemic stroke motor function |
| 基金项目:2025年邢台市市级科技计划自筹经费项目（2025ZC070） |
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| 中文摘要: |
| 目的：观察经颅磁刺激联合贴扎技术治疗缺血性脑卒中患者运动功能障碍的临床疗效。方法：选取2024年6月至2025年6月在我院康复科接受治疗的缺血性脑卒中伴有运动功能障碍患者120例，采用随机数字表法将患者分为4组，每组30例，具体分组如下：A组（普通治疗组）、B组（贴扎组）、C组（经颅磁刺激组）、D组（经颅磁刺激+贴扎组）。比较各组患者治疗前后Fugl-Meyer运动功能（FMA）、Barthel指数（BI）、美国国立卫生研究院卒中量表（NIHSS）、徒手肌力检测（MMT）评分、最大收缩期血流速度（Vs）、舒张末期血流速度（Vd）、血管阻力指数（RI）和血清可溶性细胞间黏附分子-1（sICAM-1）、超敏C反应蛋白（hs-CRP）和白细胞介素-6（IL-6）水平。结果：治疗后，B、C、D组患者的FMA、BI以及屈肘肌群和前臂旋前肌群MMT评分均高于A组（P<0.05）、NIHSS评分低于A组（P<0.05）；D组患者的FMA、BI、肘屈曲肌组和前臂旋前肌组评分高于B组和C组（P<0.05）、NIHSS评分低于B组和C组（P<0.05）；B组和C组在FMA、BI、NIHSS、屈肘肌群和前臂旋前肌群MMT评分比较差异无统计学意义。治疗后，B、C、D组患者的RI均低于A组（P<0.05），Vs、Vd均高于A组（P<0.05），D组患者的RI均低于B组和C组（P<0.05），Vs、Vd均高于B组和C组（P<0.05）；B组和C组患者的RI、Vs、Vd比较差异无统计学意义。治疗后，B、C、D组患者血清中sICAM-1、Hs-CRP和IL-6水平均低于A组（P<0.05），D组患者血清中sICAM-1、Hs-CRP和IL-6水平低于B组和C组（P<0.05），B组和C组患者血清中sICAM-1、Hs-CRP和IL-6水平比较差异无统计学意义。结论：经颅磁刺激联合贴扎技术在缺血性脑卒中患者中应用效果良好，能提升患者肢体运动功能和肌肉力量水平，增强日常生活能力，改善脑血流动力学，减轻炎症反应，促进神经功能恢复。 |
| 英文摘要: |
| Objective：To explore the clinical efficacy of transcranial magnetic stimulation combined with patch technique in the treatment of motor dysfunction in ischemic stroke. Methods：Totally, 120 patients with ischemic stroke accompanied by motor dysfunction who received treatment in the Rehabilitation Department of Xingtai People’s Hospital from June 2024 to June 2025 were selected. The patients were randomly divided into four groups using a random number table method, with 30 patients in each group: group A (general treatment group), group B (patch group), group C (transcranial magnetic stimulation group), and group D (transcranial magnetic stimulation + patch group). The Fugl-Meyer Assessment (FMA) scores, Barthel Index (BI) scores, National Institutes of Health Stroke Scale (NIHSS) scores, manual muscle test (MMT) scores, maximum systolic blood flow velocity (Vs), end diastolic blood flow velocity (Vd), vascular resistance index (RI), and serum levels of soluble intercellular adhesion molecule-1 (sICAM-1), high sensitivity C-reactive protein (hs-CRP) and interleukin-6 (IL-6) before and after treatment in each group were compared. Results：After treatment, the FMA, BI, elbow flexion muscle group, and forearm pronator muscle group scores of patients in groups B, C, and D were significantly higher than those in group A (P<0.05), and the NIHSS score was lower than that in group A (P<0.05). The FMA, BI, elbow flexion muscle group, and forearm pronator muscle group scores of patients in group D were significantly higher than those in groups B and C (P<0.05), and the NIHSS score was lower than that in groups B and C (P<0.05). There was no statistically significant difference in the scores of FMA, BI, NIHSS, elbow flexion muscle group, and forearm pronator muscle group between group B and group C. After the treatment, the RI of patients in groups B, C, and D was significantly lower than that in group A (P<0.05), and the Vs and Vd were significantly higher than those in group A (P<0.05). The RI of patients in group D was significantly lower than that in groups B and C (P<0.05), and the Vs and Vd were significantly higher than those in groups B and C (P<0.05). There was no statistically significant difference in RI, Vs, and Vd between groups B and C. After the treatment, the average serum levels of sICAM-1, Hs-CRP, and IL-6 in groups B, C, and D were significantly lower than those in group A (P<0.05), and those in group D were significantly lower than those in groups B and C (P<0.05). There was no statistically significant difference in the levels of sICAM-1, Hs-CRP, and IL-6 between groups B and C. Conclusion：The application of transcranial magnetic stimulation combined with patch technique has shown satisfactory results in patients with ischemic stroke, which can improve their limb motor function and muscle strength, enhance their daily living ability, improve cerebral hemodynamics, reduce inflammatory reactions, and promote neurological function recovery. |
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