Effect of Motor Relearning Program on Regional Cerebral Blood Flow (rCBF) of Rhesus Monkeys with Cerebral Ischemic Stroke |
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DOI: |
EN KeyWords: motor relearning program rhesus monkeys cerebral ischemia regional cerebral blood flow |
Fund Project:云南省科技厅-昆明医学院联合专项基金资助项目(2008CD37R) |
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EN Abstract: |
Objective: To observe the effect of motor relearning program (MRP) on regional cerebral blood flow (rCBF) of rhesus monkeys with cerebral ischemic stroke. Methods: Rhesus monkeys subject to an occlusion of the M1 segment of the right middle cerebral artery (MCA) by using electrocoagulation were trained with MRP, and single-photon emission computed tomography (SPECT) was used before and after MCA occlusion to semi-quantify the changes of rCBF. Results: MRP could greatly improve rCBF of the animals with cerebral ischemic stroke, but couldn’t change the functional asymmetry of cerebral hemispheres. Conclusion: It is possible that MRP increases cerebral blood flow in injured areas and other related areas to have a significant improvement on neurological deficits caused by cerebral ischemia. |
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