Abstract
Effect of Motor Relearning Program on Regional Cerebral Blood Flow (rCBF) of Rhesus Monkeys with Cerebral Ischemic Stroke
  
DOI:
EN KeyWords: motor relearning program  rhesus monkeys  cerebral ischemia  regional cerebral blood flow
Fund Project:云南省科技厅-昆明医学院联合专项基金资助项目(2008CD37R)
作者单位
尹勇 昆明医学院第四附属医院康复医学科昆明 650023 
谷震 昆明医学院第四附属医院康复医学科昆明 650023 
杨波 昆明医学院第四附属医院康复医学科昆明 650023 
秦冬冬 中国科学院昆明动物研究所昆明 650023 
潘雷 昆明医学院第四附属医院康复医学科昆明 650023 
甘露 昆明医学院第四附属医院康复医学科昆明 650023 
王廷华 昆明医学院神经科学研究所昆明 650023 
胡新天 中国科学院昆明动物研究所昆明 650023 
冯忠堂 昆明医学院神经科学研究所昆明 650023 
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EN Abstract:
  Objective: To observe the effect of motor relearning program (MRP) on regional cerebral blood flow (rCBF) of rhesus monkeys with cerebral ischemic stroke. Methods: Rhesus monkeys subject to an occlusion of the M1 segment of the right middle cerebral artery (MCA) by using electrocoagulation were trained with MRP, and single-photon emission computed tomography (SPECT) was used before and after MCA occlusion to semi-quantify the changes of rCBF. Results: MRP could greatly improve rCBF of the animals with cerebral ischemic stroke, but couldn’t change the functional asymmetry of cerebral hemispheres. Conclusion: It is possible that MRP increases cerebral blood flow in injured areas and other related areas to have a significant improvement on neurological deficits caused by cerebral ischemia.
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