| Relationship Between Homocysteine, Folate,Vitamin B12 and Vascular Dementia |
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| EN KeyWords: vascular dementia homocysteine relationship |
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| EN Abstract: |
| Objective: To investigate the relationship between plasma homocysteine (Hcy), folate,vitamin B12 and vascular dementia (VaD). Methods: The plasma levels of Hcy, folate, vitamin B12 and MMSE were measured in 86 VaD patients, 87 non-VaD cerebral vascular disease patients, and 90 age-matched normal controls of Affiliated Hospital, North China Coal Medical University.Results: The plasma Hcy levels were significantly increased in the VaD group than non-VaD cerebral vascular disease group and normal controls (P<0.01). The Hcy level was negatively related with folate and VitB12 levels. They all significantly correlated with VaD and the MMSE score (P<0.01). Conclusion: The levels of Hcy, folate and vitamin B12 were significantly correlated with VaD. |
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