| Objective: To explore the rehabilitation effect of biofeedback training combined with mirtazapine on the post-stroke depression. Methods: Sixty-six cases of post-stroke depression were randomly divided into biofeedback training combined mirtazapine group (combined group) and mirtazapine group. Both groups were given mirtazapine, and combined group was given biofeedback training additionally. Hamilton depressive scale (HAMD) and depression self rating scale (SDS) were used to assess the curative effectiveness at 1st, 2nd, 4th, and 6th week after treatment. Results: At 1st week after treatment, HAMD and SDS scores in combined group was decreased obviously as as compared with those before treatment (P<0.05) and in mirtazapine group (P<0.05). At 2nd week after treatment, HAMD and SDS scores in mirtazapine group were decreased obviously as compared with those before treatment (P<0.01). At 6th week after treatment, HAMD and SDS scores in both groups were decreased obviously (P<0.01). There was no significant difference in the efficiency between combined group and mirtazapine group (85.29% vs. 84.37%). Conclusion: Auxiliary biofeedback training can improve rehabilitation effect of post-stroke depression and is worth to being applied in clinical practice. |
