| Clinical efficacy of donepezil combined with language training for post-stroke aphasia |
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| DOI： |
| EN KeyWords: post-stroke aphasia Donepezil |
| Fund Project:广东省科技计划项目，广州市重大民生专项（No.2012Y2-00023） |
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| EN Abstract: |
| Objective:To evaluate the efficacy of donepezil combined with language training for post-stroke aphasia (PSA).Methods:Sixty patients with PSA were divided into observation group and control group randomly.Both groups were treated by language disorder ZM2.1.The observation group received treatment of donepezil hydrochloride additionally.All patients were assessed by Chinese Rehabilitation Research Center Standard Aphasia Examination (CRRCAE) before and at the endpoint of treatment respectively.Results:The scores of CRRCAE in observation group were higher than pretreatment except cartoon show,and the scores of CRRCAE in control group were higher than pretreatment,except sentences reading(all P＜0.05).And the noun-naming ability in observation group was improved more significantly than in control group (P<0.05).Conclusion:Language function of PSA could be improved by rehabilitation treatment of language disorder ZM2.1,and donepezil combined with language disorder ZM2.1 may have more efficacy in noun-naming ability. |
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