| Objective:To observe the changes of urinary function in rat urinary retention model with spinal cord injury,and explore the action mechanism of electroacupuncture and magnetic stimulation of the sacral nerve roots for urinary intenstion in early spinal cord injury.Methods：Fifty SD rats were randomly divided into 5 groups:normal group, model group,electroacupuncture group,magnetic stimulation group,and combination therapy group (n=10 each).The spinal cord injury model was established by the heavy objects falling method.The rats in model group were subjected to modeling only without any treatment,those in normal group were not subjected to modeling and treatmen,those in electroacupuncture group given electric acupuncture,and those in magnetic stimulation group were treated by magnetic stimulation.The rats were anesthetized by intraperitoneal injection of chloral hydrate.Rat bladder capacity,leakage point pressure and bladder compliance were measured.Results：After treatment for 10 times,the bladder capacity and bladder compliance in the model group were significantly increased as compared with other groups (P<0.05),and those in the combination therapy group were significantly reduced as comapred with the electroacupuncture group and the magnetic stimulation group (P<0.05).The leakage point pressure in the model group was significantly lower than other groups (P<0.05),and that in the combination therapy group was significantly lower than the electroacupuncture group and the magnetic stimulation group (P<0.05).Conclusion:Both electroacupuncture and magnetic stimulation therapy could significantly alleviate the urinary retention in early spinal cord injury,and electroacupuncture combined with magnetic stimulation treatment can obtain more satisfactory effectiveness. |
