Abstract
Clinical research on location by electrical stimulation guidance for botulinum toxin injection in the treatment of muscle spasticity
  
DOI:
EN KeyWords: botulinum toxin type A  electrical stimulation location  manual palpation-guided location
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作者单位
陈庆梅 苏州大学附属第一医院康复科苏州 215006 
孙海伟 苏州大学附属第一医院康复科苏州 215006 
李莉 苏州大学附属第一医院康复科苏州 215006 
张大伟 苏州大学附属第一医院康复科苏州 215006 
杨卫新 苏州大学附属第一医院康复科苏州 215006 
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EN Abstract:
  Objective:To observe the clinical value of electrical stimulation guidance for botulinum toxin injection.Methods:Forty-five stroke patients with spasm were selected.These patients were divided into the biceps brachii group and lower extremity groups according to the different spasm parts.The patients in the biceps brachii group were assigned into electrical stimulation subgroup (subgroup A1) (n=18) subject to electrical stimulation directing injection,and manual palpation-guided subgroup(subgroup A2) (n=17) to manual palpation-guided location.The patients in the lower extremity group were assigned into electrical stimulation subgroup(group B1) (n=20) and manual palpation-guided subgroup(group B2) (n=20).Modified Ashworth Scale(MAS),Intergrated EMG(IEMG),Passive Range of Motion(PROM),Fugl-Meyer Motor Function Assessment(FMA) and speed of gait were applied before and after treatment.Results:In subgroups A1 and A2,the measurement indexes of MAS and IEMG showed a gradual decrease after treatment(P<0.05),and the indexes in subgroup A1 were lower than in subgroup A2(P<0.05).In subgroups A1 and A2,the measurement indexes of PROM and FMA showed a gradual increase after treatment(P<0.05),and the PROM at the 4th,8th and 12th week,and the FMA at the 8th and 12th week after treatment in subgroup A1 were increased significantly as compared with subgroup A2(P<0.05).In subgroups B1 and B2,the measurement indexes of MAS,IEMG and speed of gait showed a gradual decrease after treatment(P<0.05),and PROM and FMA showed a gradual increase after treatment(P<0.05).As compared with subgroup B2,the PROM at the 2nd,and the FMA at the 12th week in subgroup B1 were increased significantly(P<0.05).There was no statistically significant difference in the variations of measurement indexes during follow-up periods between two groups.Conclusions:In biceps brachii,electrical stimulation location guidance for botulinum toxin injection got more satisfactory clinical results than the manual palpation-guided in treatment of muscle spasticity;In gastrocnemius,soleus and posterior tibial muscle,the clinical effects of electrical stimulation positioning botox injections in the treatment of muscle spasticity showed no statistically significant difference in comparison to manual palpation-guided location.
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