| Modutory effect of electroacupuncture at "Fenglong"（ST40）on blood lipid and inflammatory factors in livers of rat hyperlipidemia model |
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| DOI： |
| EN KeyWords: hyperlipemia electroacupuncture Point ST40 (Fenglong) TNF-α IL-1β IFN-γ |
| Fund Project:国家自然科学基金项目（30873309） |
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| EN Abstract: |
| Objective: To study the modutory effect of electroacupuncture at the "Fenglong" on inflammatory factors in the livers of rat hyperlipidemia model. Methods: Thirty health male SD rats were selected and randomly divided into 3 groups: normal control group (A), model control group (B), and electroacupuncture group (C). After four weeks, blood lipids of rats were determined. The protein levels of TNF-α, IL-1β and IFN-γ in the livers of rat hyperlipidemia model were detected by ELISA. Results: As compared with group A, the contents of TC, TG and LDL-C were significantly increased (P<0.01, or P<0.05) and the content of HDL-C was significantly decreased (P<0.05) in group B, and the contents of TC and LDL-C were significantly increased in group C (P<0.01). As compared with group B, the contents of TC, TG and LDL-C were significantly reduced (P<0.01), and those of HDL-C significantly increased in group C (P<0.05). As compared with group A, TNF-α, IL-1β and IFN-γ levels were increased significantly in group B (P<0.05, and P<0.01). As compared with group B, TNF-α, IL-1β and IFN-γ levels in group C were decreased significantly (P<0.05, and P<0.01). Conclusion: Electroacupuncture at "Fenglong" can notably decrease the levels of TC and LDL-C, and the protein levels of TNF-α, IL-1β and IFN-γ in the liver tissues, suggesting its certain therapeutical effectiveness on hyperlipemia. |
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