| The clinical and rehabilitation prognostic analysis of hemorrhage transformation in acute ischemic stroke |
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| EN KeyWords: ischemic stroke combined use of aspirin and clopidogrel hemorrhage transformation rehabilitation treatment |
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| EN Abstract: |
| Objective: To study if the combined use of aspirin and clopidogrel increases the risk of hemorrhage transformation (HT) and the prognostic value of early rehabilitation treatment in ischemic stroke patients. Method: 654 patients with ischemic stroke were collected to descriptively analyze the rate of HT, and to observe if the combined use of aspirin and clopidogrel increased the HT risk. Thirty patients were screened in all 55 HT patients and divided into two groups according to the illness degree and age factors: 15 not subject to rehabilitation therapy as control group, and 15 subject to rehabilitation therapy as observation group. The national institute of health stroke scale (NIHSS) and modified Rankin scale (mRS) were compared in two groups before and 14 days after treatment. Results: HT occurred in 55 cases out of 654 patients (8.41%). The combined use of aspirin and clopidogrel could not increase the HT risk. NIHSS scores were significantly decreased in both groups after 14-day treatment (P<0.05) without inter-group differences. The mRS scores were significantly increased after 14-day rehabilitation therapy in observation group as compared with the control group (P<0.05). Conclusion: HT is one of common complications in acute ischemic stroke possibly affecting the prognosis. Rehabilitation therapy can promote the neurological function recovery to some extent. |
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