| Objective: To compare the amplitude of low frequency fluctuation (ALFF) in acute phase and postherpetic neuralgia (PHN) phase of patients with trunk herpes zoster by the function magnetic resonance imaging (fMRI) technique, and to describe the brain neural functions of patients with herpes zoster at different phases by the neuroimaging. Methods: Six cases of herpes zoster were scanned by fMRI at two different phases, and the ALFF data were obtained by a statistics software. The data were used to evaluate the changes of activated cerebral regions at different phases of herpes zoster. Results: As compared with the patients at acute phase, ALFF values were reduced in the left anterior cingulate cortex (ACC), bilateral insula, bilateral cerebellum, and left fusiform gyrus in those at PHN phase. Conclusion: The ACC, insula, and cerebellum may participate in the mechanism of PHN in patients with trunk herpes zoster. |
