| Objective: To investigate the clinical curative effect of the repetitive transcranial magnetic stimulation (rTMS) in the treatment of post-stroke depression. Methods: 150 cases of post-stroke depression were randomly and equally divided into two groups: observation group and control group. The two groups were given conventional drugs, rehabilitation training and psychological counseling therapy. The observation group was subjected to rTMS in the dorsolateral prefrontal cortex (DLPFC). The Hamilton depression scale (HAMD-17), Barthel index, and stroke impact scale (SIS) score were used to evaluate the effect. Results: After the treatment for 6 weeks, HAMD-17 scores were significantly lower than those before treatment in two groups(P<0.05), more significantly in the observation group than in the control group (P<0.05). Barthel index and SIS scores were significantly increased in two groups (P<0.05), which were higher in the observation group than in the control group (P<0.05). At 12th week, the HAMD-17 scores in the control group were decreased slightly as compared with those at 6th week, but there was no statistically significant difference between two groups. On the contrary, the HAMD-17 scores after treatment for 12 weeks were decreased obviously in the observation group as compared those at 6th week and in the control group (P<0.05). The Barthel index and SIS scores were increased slightly at 12th week in the control group as compared with those at 6th week, but there was no statistically significant difference between two groups. On the contrary, the Barthel index and SIS scores were increased obviously after treatment for 12 weeks in the observation group as compared with those at 6th week and in the control group (P<0.05). Conclusion: The degree in patients with post-stroke depression was negatively correlated with the self-care ability of daily life and quality of life. rTMS in post-stroke depression patients has satisfactory effectiveness. |
