| Objective: To explore the clinical effectiveness of mild-to-moderate comorbidity of depression and anxiety by transcranial direct current stimulation. Methods: Forty-nine cases of comorbidity of depression and anxiety patients were divided into the observation group and the control group by using random number, separately given the treatment of transcranial direct current stimulation and sham stimulation. The HAMA and HAMD scores before and after treatment, clinical effectiveness and the side-effects were observed. Results: Compared with before treatment, HAMA and HAMD scores in observation group were significantly reduced after treatment for 1 week (P<0.05), and continuously decreased at 2nd and 4th week after treatment (P<0.05); those in control group were significantly decreased at 2nd week after treatment, and those at 4th week after treatment were lower than those at 2nd week (P<0.05). At 1st, 2nd, and 4th week after treatment, the HAMA and HAMD scores in observation group were obviously lower than in the control group (P<0.05). The total effective rate in observation group was significantly higher than in the control group (P<0.05). There was no significant differences in complications between two groups. Conclusion: Transcranial direct current stimulation has an obvious therapeutic effect and high safety in the treatment of mild-to-moderate comorbidtiy of depression and anxiety patients. |
