Objective: To evaluate the clinical efficacy of comprehensive treatment plus hyperbaric oxygen therapy on spontaneous intracerebral hemorrhage patients. Method: 680 cases of spontaneous intracerebral hemorrhage admitted in Wuhan Brain Hospital from January 2011 to May 2015 were selected as the study group, and 590 cases from January 2004 to December 2010 served as the control group. Control group was given decompressive craniectomy, drilling drainage, or ventricular drainage and other comprehensive treatments. Study group received hyperbaric oxygen therapy on the basis of comprehensive treatment. Clinical efficacy, mortality, activities of daily living and motor function were evaluated before and after treatment. Result: The total effective rate in the study group was significantly higher than that in the control group (P<0.05). The mortality rate in the study group was significantly lower than that in the control group (P<0.01). The GCS scores, limb motor function scores (Fugl-Meyer motor function score, FMA) and activities of daily living scores (Modified Barthel index, MBI) showed no significant difference between two groups before treatment (P>0.05). After treatment, the scores in the two groups were significantly lower than those before treatment (P<0.05), and the scores in the study group were significantly higher than those in the control group (P<0.01). Conclusion: On the basis of the comprehensive therapy, the use of hyperbaric oxygen therapy on patients with spontaneous intracerebral hemorrhage can effectively improve the curative efficacy, reduce mortality and improve prognosis. |