Objective: To explore one-year efficacy of social skill training in the treatment of residual schizophrenics. Methods: The patients were divided into research group and control group by a random number table. The patients in the research group were treated with the combination of risperidone tablets and social skill training, and those in the control group were treated with risperidone tablets alone. The prospective observational study method and the integrated case management were used during the one-year follow-up period. Two groups were assessed with Positive and Negative Syndrome Scale (PANSS), Activity of Daily Living Scale (ADL) and Social Disability Screening Schedule (SDSS) for the evaluation of psychiatric symptoms, daily life ability and social function defects, respectively. Results: Repeated measures analysis of variance showed that the PANSS total scores, negative scores, general psychopathology scores, ADL total scores and SDSS total scores in the research group were descended linearly with time. Furthermore, the trends of negative scores, ADL total scores and SDSS total scores showed significant differences in the research group as compared with the control group (P<0.05 or 0.01). As compared with the baseline, significant differences were detected in the total scores of PANSS, ADL, SDSS and PANSS negative scores at 3rd, 6th, 9th or 12th month after treatment in the research group (P<0.01). As compared with the control group, PANSS total scores decreased significantly in the research group at 12th month after treatment (P<0.05). In addition, PANSS negative scores were also decreased significantly at 9th or 12th month after treatment (P<0.01). ADL and SDSS total scores in the research group were lower than those in the control group at each different time point (P<0.05 or P<0.01). Conclusion: Systematic and normative social skill training can not only improve the general condition, negative symptom, daily life ability and social function of the residual schizophrenia patients, but also keep the improvement within one year. |