| Objective: To investigate the efficacy of comprehensive rehabilitation intervention on schizophrenia patients in community. Methods: All 104 patients with chronic schizophrenia were randomly divided into intervention group (receiving a combined hospital, community and family comprehensive rehabilitation intervention) and control group (receiving regular community mental health services). All patients were followed up for one year and assessed with the Positive and Negative Syndrome Scale (PANSS), the Chinese Cognitive Ability Scale (CCAS), the Schizophrenia Quality of Life Scale (SQLS) and the Family Interview Schedule (FIS) before and one year after the follow-up. Results: At the end of 1 year after treatment, the total and each factor scores of PANSS, CCAS, SQLS, SDSS and FIS score in intervention group were all improved significantly as compared with those before treatment (P<0.05, or <0.01). The total and general mental pathological factor scores of PANSS, and of the two factors of SQLS including psychosocial facet and motivation and energy in the control group were improved significantly (P<0.05, or <0.01), while the other scores had no obvious change. The total and negative factor scores of PANSS, operating factor scores of CCAS, the total scores of SQLS and two factors including psychosocial facet and motivation and energy in the intervention group were all significantly improved as compared with those in the control group after 1-year treatment (P<0.05, or <0.01). At the same time, there were no statistical differences in the relapse and hospitalization rate between the two groups. Conclusion: Comprehensive rehabilitation intervention can significantly improve the clinical symptoms and promote the cognitive function, at the same time can improve the quality of life, and reduce the family burden of schizophrenia patients in community. |
