Objective: To observe the transcranial direct current stimulation (tDCS) to cooperate with the clinical curative effect of psychological intervention on patients with postpartum depression (PPD). Methods: Using randomized method, 120 patients with PPD were randomly divided into three groups, 40 cases in each group. The tDCS group was given tDCS, psychological intervention group was given psychological intervention, and combination group was given psychological intervention and tDCS. After treatment for 6 weeks, the clinical curative effect, SDS, SAS and HAMD scores were observed. Results: After treatment for 6 weeks, the SAS, SDS and HAMD scores in all three groups were significantly reduced as compared with those before treatment (P<0.01). The SAS, SDS and HAMD scores in combination group were significantly lower than in tDCS group and intervention group (P<0.01). The SAS and SDS scores were significantly lower in the intervention group than in the tDCS group (P<0.01). There was no significant difference in the HAMD scores between the tDCS group and intervention group. After treatment, the total effective rate in the combination group was significantly higher than in the intervention group and tDCS group (97.5% vs. 85.0% vs. 82.5%, P<0.05), but there was no significant difference between the tDCS group and intervention group. Conclusions: The tDCS combined with psychological intervention can significantly improve the clinical curative effect of patients with PPD, decrease the HAMD scores, and significantly reduce SAS and SDS scores. |