| Objective: To investigate the quality of life (QOL) in adult patients with haemophilia and the influencing factors. Methods: Seventy-two male adult patients with haemophilia were recruited. Their quality of life (QOL), activities of daily living (ADL) and joint health status were assessed respectively using the short form-36 health survey (SF-36), the functional independence score in haemophilia (FISH) and the haemophilia joint health score (HJHS). Results: The average SF-36 score in all patients was 422.04±143.19. The score of role limitations due to physical health (RP) which was 20.21±12.96, was the lowest. There was a positive correlation between the total SF-36 score and the PF score with the FISH score and the level of education (P<0.05). There was a negative correlation between the total SF-36 score with the number of joint hemorrhage, the scores of total HJHS, muscle strength around joints, joint pain, crepitus and range of motion (ROM) (P<0.05). There was also a negative correlation between the PF score with the patients' age, the number of joint hemorrhage and muscle hemorrhage, the scores of total HJHS, muscle strength around joints, gait, joint pain, crepitus and ROM (P<0.05), with a high Pearson correlation coefficient in HJHS and muscle strength. Conclusions: The QOL was low in adult patients with haemophilia. The number of affected joints, joint health status, ADL and the degree of education were closely related to the QOL and the PF. Reducing joint hemorrhage, improving joint health status, in particular, strengthening muscles, improving the ability of ADL and the degree of education may be helpful to improve patients' QOL. |
