| Objective: To observe the effectiveness of comprehensive rehabilitation measures in combination with ɑ-lipoic acid in the treatment of shoulder-hand syndrome (SHS) after stroke. Methods: Sixty patients with SHS after stroke were randomly divided into observation group and control group, 30 cases in each group. Two groups were given routine comprehensive rehabilitation treatments, and the observation group were subjected to ɑ-lipoic acid treatment additionally. Before and after treatment, two groups were assessed with Fugl-Meyer for the upper limb movement function, visual analog score (VAS), the degree of edema, modified Barthel index (MBI). Results: Four weeks after treatment, scores of FMA and MBI were significantly increased in both groups and those in observation group were significantly higher than in the control group (P<0.05). VAS score and the degree of swelling were obviously decreased (P<0.05) in two groups, and those in the observation group were markedly lower than in the control group (P<0.05). Conclusion: Comprehensive rehabilitation in combination with ɑ-lipoic acid has synergic effects in the treatment of SHS after stroke, and can improve the effect of rehabilitation and promote the limb function recovery. |
