Objective: To observe the improvement of various therapeutic indexes by cardiac rehabilitative exercise for maintenance hemodialysis (MHD) patients with cardiac insufficiency. Methods: A total of 63 patients with chronic renal failure combined with cardiac insufficiency, who accepted MHD treatment (> 3 months) were successively selected, and they were divided into the rehabilitative exercise group (n=32) and the control group (n=31) according to the time of enrollment and the method of random number table. The patients in the rehabilitative exercise group were given the treatment of cardiac rehabilitation exercise during the intermission of MHD, including designing the reasonable exercise prescription according to the results of the 6-min walking test; gradually increasing the exercise amount from a low amount; and always following up and monitoring the changes in the blood pressure, heart rate and body mass of the patients. The patients in the control group were subjected to the routine treatment of MHD. The subjects in both groups were assessed by ultrasonic cardiogram, the dialysis adequacy indexes and exercise tolerance, and kidney disease questionnaire (KDQ) at enrollment and after 6 months. Results: The left ventricular end-systolic dimension (LVEDs), left ventricular end-diastolic dimension (LVEDd), left ventricular mass index (LVMI), cardiac index (CI), and ejection fraction (EF) after treatment for 6 months in the rehabilitative exercise group were all obviously superior to those at enrollment and those in the control group at the same period (P<0.01, <0.05). There was no significant difference in the distribution of indexes of exercise tolerance and dialysis adequacy at enrollment between two groups, and the distances of the 6 min walking test after 6 months in the rehabilitative exercise group were all obviously longer than those at enrollment and those in the control group at the same period (P<0.01, <0.05). The sub time scores and the total score of the KDQ at enrollment showed no significant difference between two groups (P>0.05), and most sub-time scores and the total score of the KDQ after 6 months in the rehabilitative exercise group were all obviously higher than those at enrollment and those in the control group at the same period (P<0.01, <0.05). Conclusion: Cardiac rehabilitative exercise can obviously ameliorate various therapeutic indexes of MHD patients with cardiac insufficiency. |