Clinical Study on Electrophysiological Changes of Phrenic Nerve and Inspiratory Function in Patients with Stroke |
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DOI: |
EN KeyWords: stroke electrophysiology phrenic nerve diaphragm inspiratory function |
Fund Project:苏州市临床医学专家团队引进A类项目资助(SZYJTD201725) |
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EN Abstract: |
Objective: To investigate the characteristics of electrophysiological changes of phrenic nerve and inspiratory function in patients with stroke. Methods: Phrenic nerve motor conduction and inspiratory function were tested in 42 healthy subjects and 86 patients with stroke. Results: As compared with the control group, the inspiratory strength index, the inspiratory peak velocity and the suction volume decreased significantly in stroke group (P<0.05). The latency of phrenic nerve motor conduction in affected side of stroke group was prolonged obviously as compared with the contralateral side and control group (P<0.05), but there were no significant differences between unaffected side and control group (P>0.05). The amplitudes of phrenic nerve motor conduction in the unaffected side were higher obviously than in the contralateral side and control group (P<0.05), but there were no significant differences between the affected side and control group (P>0.05). The patients with stroke needed greater minimum electrical stimulation intensity to obtain maximum waveform than control group (P<0.05). Conclusions: The inspiratory function decreased significantly poststroke. And the latency of phrenic nerve motor conduction in the affected side is prolonged significantly, and excitability reduced in stroke group. The electrophysiological detection may provide objective evidence for diaphragmatic function evaluation after stroke. |
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