Abstract
Clinical Study on Electrophysiological Changes of Phrenic Nerve and Inspiratory Function in Patients with Stroke
  
DOI:
EN KeyWords: stroke  electrophysiology  phrenic nerve  diaphragm  inspiratory function
Fund Project:苏州市临床医学专家团队引进A类项目资助(SZYJTD201725)
作者单位
周停 1.南京医科大学第一附属医院康复医学中心南京 2100293.南京医科大学附属江苏盛泽医院南京 210029 
王培 2.上海交通大学附属同仁医院南京 210029 
李卫卫 3.南京医科大学附属江苏盛泽医院南京 210029 
苏彩霞 3.南京医科大学附属江苏盛泽医院南京 210029 
王红星 1.南京医科大学第一附属医院康复医学中心南京 2100293.南京医科大学附属江苏盛泽医院南京 210029 
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EN Abstract:
  Objective: To investigate the characteristics of electrophysiological changes of phrenic nerve and inspiratory function in patients with stroke. Methods: Phrenic nerve motor conduction and inspiratory function were tested in 42 healthy subjects and 86 patients with stroke. Results: As compared with the control group, the inspiratory strength index, the inspiratory peak velocity and the suction volume decreased significantly in stroke group (P<0.05). The latency of phrenic nerve motor conduction in affected side of stroke group was prolonged obviously as compared with the contralateral side and control group (P<0.05), but there were no significant differences between unaffected side and control group (P>0.05). The amplitudes of phrenic nerve motor conduction in the unaffected side were higher obviously than in the contralateral side and control group (P<0.05), but there were no significant differences between the affected side and control group (P>0.05). The patients with stroke needed greater minimum electrical stimulation intensity to obtain maximum waveform than control group (P<0.05). Conclusions: The inspiratory function decreased significantly poststroke. And the latency of phrenic nerve motor conduction in the affected side is prolonged significantly, and excitability reduced in stroke group. The electrophysiological detection may provide objective evidence for diaphragmatic function evaluation after stroke.
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