| Effects of extracorporeal shock wave therapy combined with botulinum toxin type A on motor function and physical activity in children with spastic cerebral palsy |
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| DOI： |
| EN KeyWords: cerebral palsy spasticity physical activity extracorporeal shock wave botulinum toxin |
| Fund Project:广东省医学科学技术研究基金项目（A2016415） |
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| EN Abstract: |
| Objective: To investigate the effect of extracorporeal shock wave (ESW) therapy combined with botulinum neurotoxin A (BoNT A ) on motor function and physical activity in children with spastic cerebral palsy. Methods: Sixty children with spastic cerebral palsy (2 10 years old) were randomized into control group and treatment group. Participants in both groups received BoNT A injection into triceps surae muscle of the affected limbs and regular rehabilitation therapy simultaneously. Additionally, the treatment group received ESW therapy 24 h after BoNT A injection. Modified Ashworth Scale (MAS), Gross Motor Function Measure (GMFM) and physical activity were assessed before and 3 months after treatment. Results: The scores of MAS decreased, and scores of GMFM at D and E regions increased in both groups after treatment (all P<0.05). These changes of MAS and GMFM D scores were more significant in treatment group than in control group (P<0.05). Both groups spent less percentage of time in sedentary behavior and more percentage of time in light activity after treatment (all P<0.05), and these changes were more significant in the treatment group than in the control group (P<0.05). Conclusion: Compared to BoNT A injection alone, its combination with ESW therapy can release muscle spasm, improve gross motor function and physical activity level more effectively in children with spastic cerebral palsy. |
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