Objective: To investigate the effect of group cognitive behavioral therapy in the treatment of generalized autobiographical memory in patients with mild depression and its impact on QOL scores. Methods: 120 patients with mild depression who were admitted to our hospital from June 2016 to December 2017 were enrolled. According to the treatment plan, they were divided into control group and observation group equally. The control group was treated with drugs. The observation group was given drugs combined with group cognitive behavioral therapy. The two groups were treated for 3 weeks. The effect of the patients was evaluated after the treatment. The Beck Depression Scale (BDI) and Williams Autobiographical Gene (AMT) experimental paradigm were evaluated and counted before and 3 weeks after treatment. The quality of life (QLQ C30) scale was used to assess the two groups before and after treatment. The physiological function, physiological intelligence, physical pain, overall health, vitality, social function, emotional intelligence and mental health quality of life were assessed after treatment for 3 weeks. The hospital self study questionnaire was used to evaluate the treatment compliance in the two groups. The impact of group cognitive behavioral therapy on QOL scores was analyzed. Results: There was no significant difference in BDI score between the observation group and the control group before and after treatment (P>0.05). The positive score of AMT was significantly higher in the observation group than in the control group (P<0.05). The positive scores in the last 3 weeks were lower than those in the control group (P<0.05). The physiological function, physiological intelligence, physical pain, general health, vitality, social function, emotional intelligence and mental health scores in the observation group were higher than those in the control group after treatment for 3 weeks (P<0.05). The treatment compliance rate in the observation group after cognitive treatment was 95.00%, significantly higher than that in the control group (88.33%; P<0.05). Conclusion: The use of group cognitive behavior therapy for the treatment of patients with mild depression with generalized autobiographical memory is effective, which can improve the autobiographical memory, the quality of life and compliance of patients. It is worthy of popularization and application. |