| Objective: To explore the clinical efficacy of respiratory functional rehabilitation training in patients with frequent acute exacerbation asthma COPD overlap syndrome (ACOS). Methods: A total of 48 cases of frequent acute exacerbation ACOS were selected as the research subjects, and were divided into control group and observation group by random number table, 24 cases in each group. All patients in control group and observation were given normal therapy and healthy education, and those in observation group received respiratory functional rehabilitation training additionally, and the training time was 12 weeks. The parameters including respiratory rate (RR), arterial blood oxygen content, pulmonary function, respiratory muscle strength, exercise endurance, degree of dyspnea and quality of life, as well as anxiety and depression scores were measured before and 12 weeks after therapy, and the acute exacerbation frequency, times of hospitalization and medical cost within 1 year before and after the treatment were also recorded. All the clinical data were recorded to assess and compare the therapeutic effects of the two groups. Results: After 12 weeks of respiratory functional rehabilitation training, RR and PaCO2 in observation group were dramatically lower than those in control group (both P<0.05), while PaO2 and SaO2 were obviously higher than those in control group after training (both P<0.05). The pulmonary function indexes and the respiratory muscle strength indexes in observation group after training were significantly higher than those in control group except IC (all P<0.05). After training, 6 MWD in observation group was significantly increased as compared with that in control group, while mMRC and SGRQ total scores were significantly lower in observation group than those in control group after training (all P<0.05). The anxiety and depression scores and total scores in observation group were significantly lower than those in control group after training (all P<0.05). After training, the acute exacerbation frequency, times of hospitalization and medical cost within 1 year in observation group were dramatically reduced as compared with those in control group (all P<0.05). Conclusion: Respiratory functional rehabilitation training can effectively relieve the dyspnea symptoms in patients with frequent acute exacerbation ACOS, enhance respiratory muscle strength and exercise endurance, improve anxiety and depression emotion and the quality of life of patients, reduce the recurrence rate of ACOS, and lighten the economic burden on patients. |
