| Objective: The aim of this study was to evaluate the effect of mirror neuron training system combined with low-frequency rTMS in the homologous area on the aphasia patients with cerebrovascular disease (CVD). Methods: A total of 50 patients with global aphasia after stroke in the Department of Rehabilitation Medicine of Nanjing Brain Hospital were randomly divided into control group, MNS group and low-frequency rTMS+MNS group. The control group was only given routine speech rehabilitation training, the MNS group was given mirror neuron training on the basis of the control group, and the low-frequency rTMS+MNS group was given rTMS (1 Hz) stimulation of the right Broca homologous region on the basis of the MNS treatment group, twice a day, 6 times a week. Western Aphasia Battery (WAB) and Boston aphasia rating scale (BDAE) were evaluated before and 3 weeks after treatment. Results: There was no significant difference in WAB score and BDAE score among the three groups before treatment. After treatment, the scores of WAB and BDAE were significantly higher than those before treatment (P<0.05), and the scores of spontaneous language, repetition, naming, AQ, information and BDAE in the low-frequency rTMS+MNS group were significantly higher than those in the MNS group and the control group (P<0.05). The scores of spontaneous language, repetition, naming and AQ in the MNS group were also significantly higher than those in the control group (P<0.05). Conclusion: Action observation therapy combined with inhibitory rTMS of right Broca homologous region can improve the language function of patients with global aphasia after stroke. |
