Objective: To investigate the clinical effect of isokinetic muscle strength training on improving muscle function in knee osteoarthritis. Methods: The CNKI, VIP, Wanfang and PubMed databases were searched by computer from August 2008 till now, and randomized control trials (RCTs) on isokinetic muscle strength training which could improve muscle function in KOA were selected. After screening, data extraction, quality evaluation and risk assessment, meta analysis was carried out with RevMan 5.3 software. Results: A total of 10 studies were included, and there were 718 cases. Isokokinetic muscle training could improve muscle function better than the control group, such as LKSS score (MD = 9.41, 95% CI [5.63, 13.19], Z=4.88, Z=4.88, P<0.05), LKSS score (MD = 9.41, 95% CI [5.63, 13.19], Z=4.88, Z=4.88, P<0.05), extensor peak torque (MD = 20.31, 95% CI [8.48, 32.48, 32.15], Z=3.36, P<0.05, P<0.05), flexor peak torque (MD = 14.32, 95% CI 95% CI [3.32, 95%] CI [3.37 64, 95%] CI [-1.20, -0 8], Z=2.24, P=0.02), extensor total work (MD = 86.63, 95% CI [42.48, 130.77], Z=3.85, P<0.05), flexor total work (MD = 57.85, 95% CI [38.07, 77.63], Z=5.73, P<0.05). Conclusion: Isokinetic muscle strength training can improve the muscle function to a certain extent. However, due to the limited number of literatures included, the exact conclusions still need to be verified by RCTs with large samples and high quality. |