| Objective: To observe the clinical effect of plaster tube fixation combined with botulinum toxin-A (BTX-A) injection on the functions of sitting, standing and walking, as well as the degree of muscle spasm in children with spastic cerebral palsy (CP), in order to provide theoretical basis for treatment of CP. Methods: A total of 120 children with spastic CP were randomly and equally divided into treatment group and control group. Children in control group were treated with BTX-A injection on the basis of comprehensive rehabilitation and home rehabilitation guidance, and those in treatment group were given the plaster tube fixation additionally on the basis of the control group. A total of 88 items version of gross motor function measure (GMFM-88) and parameter X of Modified Tardieu Scale (MTS) were assessed before treatment, 1 month, 3 months, and 6 months after treatment. Results: Except for the control group after 6 months of treatment, the scores of GMFM-88 in zone D were not statistically different from those before treatment. The scores of each zone of GMFM-88 in the two groups after treatment for 1 month, 3 months and 6 months were significantly higher than those before treatment (all P<0.05), and the scores of each area of GMFM-88 in the treatment group were significantly higher than those in the control group after 6 months of treatment (all P<0.05). After 1 month, 3 months and 6 months of treatment, the MTS parameter (X) scores of the triceps and hamstrings in the two groups were significantly lower than those before treatment (all P<0.05), and those in the treatment group were significantly lower than those in the control group at the same time points after 6 months of treatment (all P<0.05). Conclusion: On the basis of comprehensive rehabilitation, BTX-A injection can significantly reduce muscle tension and improve gross motor function in children with CP. Meanwhile, their combination with plaster tube fixation could prolong the long-term effect of BTX-A injection. |
