| Low-frequency repetitive transcranial magnetic stimulation for non-fluenct aphasia after stroke: a systematic review |
| |
| DOI： |
| EN KeyWords: repetitive transcranial magnetic stimulation aphasia stroke systematic review Meta-analysis |
| Fund Project:山东省中医药科技发展计划项目（2017-011）；山东省高等学校科技计划项目（J14LK08）；山东中医药大学经方治疗重大疾病作用机理与疗效评价科研创新团队基金资助项目(220316) |
|
| View Counts: 10670 |
| PDF Download Counts: 7485 |
| EN Abstract: |
| Objective: To systematically evaluate the efficacy of low-frequency repetitive transcranial magnetic stimulation (rTMS) in the treatment of non-fluenct aphasia after stroke. Methods: The PubMed, EMbase, Cochrane Library, CNKI, WanFang data, VIP and CBM databases were searched, and randomized controlled trials (RCT) of rTMS in the treatment of post-stroke aphasia were collected. The search period was from the establishment of the database to June 2020. After screening the literature, a meta-analysis of mergeable studies was performed using RevMan 5.3 software for the studies with an effect size. The rest studies were given the descriptive analysis. Results: Totally, 10 RCTs were included. Six trials used The Western Aphasia Battery-AQ (WAB-AQ) as the result indicator. The results of the meta-analysis showed that after low-frequency rTMS, the WAB-AQ score in the treatment group was higher than that in the control group ［SMD = 1.27, 95% CI (0.71, 1.82), P<0.01］. Two trials used Aphasia Battery of Chinese (ABC) scores as outcome indicators. There was no significant difference between the two groups ［MD = 6.07, 95% CI (-6.92, 19.05), P=0.36］. Conclusion: Low-frequency rTMS can effectively improve the speech function of patients with non-fluenct aphasia after stroke. However, the above conclusions still need to be verified by clinical trials with a larger number of samples or a unified evaluation scale. |
|
查看全文
Download PDF Reader HTML Full Text |
| Close |
|
|
|
