Abstract
Efficacy of percutaneous median nerve stimulation for patients with mild-moderate depression
  
DOI:
EN KeyWords: depression  transcutaneous median nerve stimulation  HAMD-24
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作者单位
林明栓 中南大学湘雅医学院附属海口医院临床心理精神科海口 570208 
李小山 中南大学湘雅医学院附属海口医院康复医学科海口 570208 
卞少珍 中南大学湘雅医学院附属海口医院康复医学科海口 570208 
王美秀 中南大学湘雅医学院附属海口医院临床心理精神科海口 570208 
符俊骐 中南大学湘雅医学院附属海口医院神经外科海口 570208 
薛志敏 中南大学湘雅二医院精神卫生研究所长沙 410011 
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EN Abstract:
  Objective: To observe the clinical efficacy of transcutaneous median nerve stimulation (MNES) for patients with mild-moderate depression. Methods: A total of 60 depressed patients admitted to our center from August 2018 to August 2019 were selected and divided into the control group (receiving conventional treatment) and the MNES group (given the right MNES on the basis of conventional treatment) according to the random number, 30 cases in each group. Both groups of patients received conventional antidepressant treatment. In the MNES group, the right MNES treatment was performed on this basis. One electrode was placed on the 2 cm median nerve point on the palmar transverse stripes of the right wrist joint, and the other was placed on the right thenar muscle; single stimulation duration of 40 s, intermittent time of 20 s, 30 min/time/day, 5 times/week, a total of 6 weeks of treatment. The Hamilton Depression Scale (HAMD-24), Self-Rating Depression Scale (SDS) and Pittsburgh Sleep Quality Index (PSQI) were used before and 3 weeks and 6 weeks after treatment to assess the depression, anxiety and sleep status of patients. Results: After 3 weeks of treatment, the HAMD-24 and SDS scores in the control group and the MNES group were significantly improved (P<0.05), and there was no significant difference between the two groups. After 3 weeks of treatment, although the PSQI score in the control group had a tendency to decrease, there was no statistical difference; after 3 weeks of treatment, the PSQI score in the MNES group was significantly lower than that before treatment (P<0.05), but there was no statistical difference between two groups. After 6 weeks of treatment, the HAMD-24, SDS and PSQI scores in the control group and MNES group were significantly improved as compared with those before the treatment (P<0.05), and the scores in the MNES group were significantly better than those in the control group (P<0.05). Conclusion: Median nerve stimulation therapy has a certain therapeutic effect on depressed patients, which can improve their depression level and sleep quality. It is recommended to promote it.
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