Objective: To explore the effect of Lee Silverman Voice Treatment (LSVT)-BIG on motor function, walking function and quality of life in patients with Parkinson’s disease. Methods: A total of 40 patients with primary Parkinson’s disease in Hoehn-Yahr stages 1-3 were selected and divided into the BIG therapy group and the conventional rehabilitation group according to the random number table method. Before treatment and after 8 weeks of treatment, the Unified Parkinson’s Disease Comprehensive Evaluation Scale, standing-walking time test (TUGT), 10-meter walking test (10MWT), 39 items of Parkinson’s disease questionnaire (PDQ-39) were used to evaluate the efficacy. Results: After 8 weeks of training, the total scores of MDS-UPDRS Ⅲ decreased (P<0.05), TUGT time shortened (P<0.05), 10-MWT time shortened (P<0.05), step length increased (P<0.05), and PDQ-39 score decreased as compared with those before treatment, indicating that conventional rehabilitation treatment and BIG therapy could improve walking function and quality of life in patients with Parkinson’s disease. The improvement of 10-MWT time, 10-MWT step length, PDQ-39 score and MDS-UPDRS Ⅲ total score in LSVT-BIG group was better than that in conventional treatment group, and the difference was statistically significant (P<0.01). Conclusions: LSVT-BIG therapy can effectively improve the walking function and quality of life of patients with Parkinson’s disease. |